10批不同栀子中两种主要环烯醚萜苷类化合物成分含量比较  

Comparison of Component Content Between two Main Compounds of Iridoid Glycoside Existing in Ten Different Gardenia Jasminoides

作　　者：王昕硕 李志雄[2] 孙兆林[2] 季宇彬[1] 

机构地区：[1]哈尔滨商业大学生命科学与环境科学研究中心,黑龙江哈尔滨150076 [2]中国科学院上海药物研究所,上海201203

出　　处：《亚太传统医药》2014年第6期24-26,共3页Asia-Pacific Traditional Medicine

摘　　要：目的:对10批不同栀子中栀子苷、京尼平龙胆双糖苷的含量进行测定并比较。方法:采用高效液相色谱法,色谱柱为Agilent Eclipse XDB-C18(4.6mm×250mm,5μm),流动相为乙腈-水(15∶85),流速为1.0mL·min-1,柱温为25℃,检测波长为238nm,同时检测2个主要成分(栀子苷、京尼平龙胆双糖苷)的含量。结果:江西早期栀子中京尼平龙胆双糖苷含量较高,四川晚期栀子中栀子苷含量较高。结论:不同产地栀子中两种环烯醚萜类化合物的含量有明显差别,说明栀子果实的生长地点、采摘时间对其中的栀子苷、京尼平龙胆双糖苷含量有较大影响。Objective：To measure the contents of Gardenoside and genipin gentiobioside in ten different batches of Gardenia Jasmi- noides. Methods. The method is to adopt Agilent Eclipse XDB-C18 chromatographic column （4.6mm ×250mm,5μm）, mobile phase： acetonitrile （15 ： 85）,column temperature： 25℃ ,measurement wavelength1238nm. At the same time, it is also to detect two main component contents （Gardenoside and genipin gentiobioside）. Results ： The contents of genipin gentiobioside in early Gardenia Jasmi- noides of Jiangxi province are higher, and the contents of Gardenoside in late Gardenia Jasminoides of Sichuan province are higher. Conclusion：The component contents of Iridoid Glycoside compound are clearly different in Gardenia jasminoides from different places of origin.

关 键 词：栀子 栀子苷 京尼平龙胆双糖苷 HPLC 

分 类 号：R284.1[医药卫生—中药学]