磷钨酸/硅胶催化合成2-乙酰噻吩  

Synthesis of 2-Acetyl Thiophene Catalyzed by Phosphotungstic Acid/Silica Gel

作　　者：朱贤江[1] 姚从兴 王丽[1] 赵学娇[1] 蔡可迎[1] 

机构地区：[1]徐州工程学院化学化工学院,江苏徐州221018

出　　处：《化工技术与开发》2014年第3期7-9,共3页Technology & Development of Chemical Industry

基　　金：国家级大学生实践创新训练计划项目(GCX2012010);徐州工程学院大学生创新创业基金项目(201317)

摘　　要：采用浸渍法制备了磷钨酸／硅胶催化剂，将此催化剂用于催化噻吩乙酰化反应合成2－乙酰噻吩，考察了磷钨酸负载量和催化剂干燥温度对催化剂活性的影响。结果表明催化剂中磷钨酸的负载量为40％、催化剂的干燥温度为120～200℃时，催化剂的活性较高。200℃干燥的催化剂具有较好的重复使用性。在适宜的条件下，噻吩与过量的乙酸酐反应，得到2-乙酰噻吩的收率达90％。The catalysts phosphotungstic acid/silica gel were prepared by impregnation for the synthesis of 2-acetyl thiophene. The influences of phosphotungstic acid loading and drying temperature on catalysts were investigated. The results showed that the catalyst with 40% phosphotungstic acid had higher activity, which was dried at 120-200 ℃, and the catalyst dried at 200 ℃ had better reusability. Under suitable conditions, 2-acetyl thiophene was synthesized from thiophene and acetic anhydride with 90% yield.

关 键 词：磷钨酸 2-乙酰噻吩 合成 

分 类 号：TQ251.2[化学工程—有机化工]