静脉滴注单硝酸异山梨脂治疗冠心病心绞痛的临床疗效观察  

Clinical Efficacy Observation of Coronary Heart Disease Combined with Angina Pectoris by Intravenous Isosorbide Sorbic

作　　者：李毓娟 

机构地区：[1]重庆市开县人民医院心血管内科,重庆405400

出　　处：《中国医药导刊》2014年第1期84-85,87,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨静脉滴注单硝酸异山梨脂治疗冠心病心绞痛的临床效果。方法:120例冠心病心绞痛患者随机分为研究组和对照组各60例,在常规治疗基础上,研究组患者给予静脉滴注单硝酸异山梨脂注射液,对照组患者给予静脉滴注硝酸甘油。结果:两组心绞痛治疗效果评价情况如表1所示,研究组患者心绞痛治疗有效率达93.33%,明显高于对照组患者心绞痛治疗有效率70%,两组数据经统计学比较具有极显著差异(P<0.01)。研究组患者心电图治疗有效率90%,明显高于对照组心电图治疗有效率75%,两组数据经统计学比较具有显著差异(P<0.05)。治疗后两组血液流变学指标均较治疗前有明显改善(P<0.05),研究组改善效果优于对照组(P<0.05)。结论:应用单硝酸异册梨脂静脉滴注治疗冠心病心绞痛具有较好的临床疗效,药物利用率更高。Objective：To investigate the clinical effect of coronary heart disease combined with angina pectoris by intravenous isosorbide sorbic.Methods：120 cases with angina pectoris combined with coronary heart disease were randomly divided into study group and control group with 60 cases in each group, on the basis of routine treatment, patients in study group were given intravenous isosorbide grease injection, and patients in control group were treated with intravenous infusion of nitroglycerin.Results：The angina and ECG effective rate of study group was significantly higher than those in control group （P〈0.05）. After treatment, two groups of hemorheology were improved significantly compared with before treatment （P〈0.05）, and study group had better results than control group （P〈0.05）. Conclusion：It has good clinical effects to treat coronary heart disease combined with angina pectoris by isosorbide lipide with intravenous drip, and it has a higher drug utilization rate.

关 键 词：静脉滴注 单硝酸异山梨脂 冠心病 心绞痛 

分 类 号：R541.4[医药卫生—心血管疾病]