Cardiac electrical activity imaging of patients with CRBBB or CLBBB in magnetocardiography  

作　　者：朱俊杰 蒋式勤 王伟远 赵晨 吴燕华 罗明 权薇薇 

机构地区：[1]Department of Control Science and Engineering, School of Electronics and Information Engineering, Tongji University [2]Department of Cardiology of Tongji Hospital Affiliated to Tongji University Medical School [3]Department of Cardiology of Ruijin Hospital Affiliated to Jiaotong University Medical School

出　　处：《Chinese Physics B》2014年第4期717-722,共6页中国物理B（英文版）

基　　金：Project supported in part by the National Natural Science Foundation of China(Grant No.60771030);the National High-Technology Research and DevelopmentProgram of China(Grant No.2008AA02Z308);the Shanghai Science and Technology Development Foundation(Grant No.08JC1421800);the Shanghai Leading Academic Discipline Project(Grant No.B004);the Open Project of State Key Laboratory of Function Materials for Information(Shanghai Instituteof Microsystem and Information Technology,Chinese Academy of Sciences);the Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention of Shanghai(Grant No.13DZ2272200-2)

摘　　要：A new method for the imaging of cardiac electrical activity in patients with complete right bundle branch block （CRBBB） or complete left bundle branch block （CLBBB） is investigated using magnetocardiographic recordings of the surface of the body. This is based on the assumption that an equivalent single-current dipole moves along the unblocked bundle branch, whose position in the measurement plane is expressed in terms of the maximum and minimum, as well as the maximum gradient value of the measured magnetic field. The trajectory of the moving dipole on the measurement plane is indicative of theexcitation conduction of the CRBBB or CLBBB subject during ventricular depolarization and repolarization, which is deduced by comparing each change between the dipole moment and the maximum current density in a corresponding pseudo-current density map. In summary, this method can distinguish CRBBB from CLBBB subjects by means of the dipole depth and two dipole moment components. The possibility of visualizing the excitation conduction in a CRBBB or CLBBB subject during ventricular depolarization and repolarization is then discussed.A new method for the imaging of cardiac electrical activity in patients with complete right bundle branch block （CRBBB） or complete left bundle branch block （CLBBB） is investigated using magnetocardiographic recordings of the surface of the body. This is based on the assumption that an equivalent single-current dipole moves along the unblocked bundle branch, whose position in the measurement plane is expressed in terms of the maximum and minimum, as well as the maximum gradient value of the measured magnetic field. The trajectory of the moving dipole on the measurement plane is indicative of theexcitation conduction of the CRBBB or CLBBB subject during ventricular depolarization and repolarization, which is deduced by comparing each change between the dipole moment and the maximum current density in a corresponding pseudo-current density map. In summary, this method can distinguish CRBBB from CLBBB subjects by means of the dipole depth and two dipole moment components. The possibility of visualizing the excitation conduction in a CRBBB or CLBBB subject during ventricular depolarization and repolarization is then discussed.

关 键 词：BIOMAGNETISM inverse problem magnetocardiography （MCG） current source reconstruction（CSR） CRBBB or CLBBB 

分 类 号：R541[医药卫生—心血管疾病] O413[医药卫生—内科学]