钙摄入与心血管疾病风险的研究进展  

Advances in research of calcium intake and cardiovascular diseases

作　　者：王锦溪[1] 李虹伟[1] 

机构地区：[1]首都医科大学附属北京友谊医院心血管中心,北京100050

出　　处：《心脏杂志》2014年第2期218-221,共4页Chinese Heart Journal

摘　　要：钙摄入对于心血管系统的健康效应正日益受到争议。尽管早期研究提示钙质可能具有心血管系统保护作用,日益增多的证据支持过量摄入膳食钙及补充钙剂可能对心血管系统产生不利影响。钙可通过上调肾素-血管紧张素-醛固酮系统、促进血管钙化、导致短期内血钙波动、引发高凝状态等多种机制影响心血管系统。钙对于心血管系统的潜在获益与风险亟需大规模试验进一步深入评估。The health effects of calcium intake on the cardiovascular system have become increasingly contentious. Despite some earlier studies suggesting a protective role of calcium against cardiovascular diseases, there is increasing evidence supporting the notion that excess dietary calcium and calcium supplements may have adverse effects on the cardiovascular system with the underlying mechanisms of upregulation of the renin-angiotensin-aldosterone system, vascular calcifieation, rise of serum calcium and hypercoagulability. The benefits and risks of calcium intake on the cardiovascular system remain to be further investigated.

关 键 词：膳食钙 补充钙剂 心血管疾病 

分 类 号：Q582[生物学—生物化学] R714.252[医药卫生—妇产科学]