实时三维超声心动图评价主动脉瓣患者手术前后左心室重构与功能  

Assessment of Left Ventricular Remodeling and Function in Patients with Aortic Valve Replacement using Real-time 3D Echocardiography

作　　者：刘园园[1] 张连仲[2] 刘琳[2] 程兆云[3] 冯德广[3] 崔存英 

机构地区：[1]郑州大学第一附属医院超声科,郑州市450000 [2]河南省人民医院心血管超声科 [3]河南省人民医院心外科

出　　处：《中国超声医学杂志》2014年第3期226-230,共5页Chinese Journal of Ultrasound in Medicine

基　　金：河南省二○一三年科技发展计划(No.112102310101);河南省医学科技攻关计划项目(No.201303178)

摘　　要：目的探讨实时三维超声心动图(RT-3DE)评价主动脉瓣置换(AVR)患者左心室重构的价值。方法 90例研究对象分为3组:主动脉瓣关闭不全组(A组),主动脉瓣狭窄组(B组),正常对照组(C组)。应用RT-3DE对AVR患者术前、术后1周、术后1个月及C组进行检查,脱机分析得出左室舒张末期容积(LVEDV)、左室射血分数(LVEF)、左室质量指数(LVMI)及左室重构指数(LVRI)等进行比较。结果三组间术前、术后1周及术后1个月LVMI和LVRI差异有统计学意义(P<0.05)。术后1周A组LVEDVI、LVESVI、LVMI及B组LVMI与术前相比,差异有统计学意义(P<0.05);术前及术后1周A组与B组LVRI相比,差异有统计学意义(P<0.05)。术后1周,AVR组LVEF与LVMI呈负相关(r=-0.75,P<0.05)。结论 RT-3DE能够评价AVR患者左心室重构与功能。Objective To assess the value of real-time 3D echocardiography （RT-3DE） in evaluating left ventric ular remodeling in patients with aortic valve replacement （AVR）. Methods Ninety patients were divided into aortic regurgitation group（Group A）, aortic stenosis group（Group B）, normal control group（Group C）. RT-3DE was per formed for study groups before operation,1 week and 1 month after operation. A series of left ventricular parameters were analyzed offline, including left ventricular end-diastolic volume （LVEDV）, left ventricular ejection fraction （LVEF） ,left ventrieular mass index（LVMI）, left ventricular remodeling index （LVRI）. Results LVMI and LVRI had significant differences in three groups before operation, 1 week and 1 month after operation（P〈0.05）. LVEDVI, LVESVI, LVMI had significant differences in Group A and LVMI in Group B after 1 week of AVR compared with pre-operation （P〈0.05）, LVRI had significant differences in Group A compared with Group B before operation and 1 week after operation （P〈0.05）. Linear correlation analysis showed negative correlation between LVEF and LVMI af ter 1 week of AVR（r=-0.75,P〈0. 05）. Conclusions RT-3DE could be a useful method to evaluate left ventricular remodeling and function in patients with AVR.

关 键 词：实时三维 超声心动图描记术 主动脉瓣病变 主动脉瓣置换 左室重构 

分 类 号：R540.45[医药卫生—心血管疾病]