极速成像技术检测的脉搏波传导速度与颈动脉硬化相关性的研究  

Evaluation of the relationship between pulse wave velocity and carotid atherosclerosis by UltraFast imaging

作　　者：邱兰燕[1] 钱林学[1] 刘冬[1] 张宏[1] 胡向东[1] 任晓转 梁思[1] 

机构地区：[1]首都医科大学附属北京友谊医院超声科,北京100050

出　　处：《中华超声影像学杂志》2014年第3期203-205,共3页Chinese Journal of Ultrasonography

摘　　要：目的探讨极速成像（UhraFastimaging）技术检测的脉搏波传导速度（pulsewavevelocity，PwV）与颈动脉硬化的相关性。方法随机抽取476例在我院行健康体检者，依据颈动脉内中膜厚度（intima—mediumthickness，IMT）分为IMT正常组283例及IMT增厚组193例。应用极速成像技术测量颈动脉PwV，包括收缩期起始时PWV（beginningofthesystole，BS）及收缩期结束时PwV（endingofthesystole，ES），灰阶超声测量颈动脉IMT及斑块情况。应用Spearman秩相关分析颈动脉IMT与弹性值BS、ES间的相关性；两独立样本t检验比较两组间BS、ES均值的差异。结果BS、ES与IMT相关性具有统计学意义，其中BS与IMT相关系数为0．192，ES与IMT相关系数为0．249。IMT增厚组BS、ES值均较IMT正常组增大[（6．03±1．33）m／s对（5．51±1．13）m／s，t=-4．571，P=0．000；（8．42±2．13）m／s对（7．34±2．02）m／s，t=5．619，P=0．000]。结论极速成像技术可快速测量颈动脉PwV，BS及ES可评估颈动脉弹性改变，有望成为一种快速、方便、安全、无创评估颈动脉硬化的新方法。Objective To assess the relationship between pulse wave velocity（PWV） and carotid atherosclerosis by UltraFast imaging. Methods 476 cases from Medical Examination Center of Beijing Friendship Hospital were enrolled in this study. According to intima-media thickness （IMT） of carotid artery,all subjects were divided into two groups：IMT without thickening group （GO） of 283 cases and IMT thickening group （G1） of 193 cases. Through UltraFast imaging, carotid artery PWV was measured, including the PWV at the beginning of the systole（BS） and the PWV at the ending of the systole（ES）. Carotid IMT and plaque situation were recorded under gray-scale ultrasound. BS and ES were compared between the two groups. Spearman rank correlation was used to analyse the correlation between IMT of carotid artery and BS,between IMT of carotid artery and ES. Two independent samples t test to compare BS,ES between the two groups. Results BS of G1 and G0 were （6.03 ± 1.33）m/s and （5.51 ± 1.13）m/s, t = - 4. 571, P = 0. 000;ES of G1 and GO were （8.42 ± 2.13）m/s and （7.34 ± 2.02） m/s, t = 5. 619, P = 0. 000. BS and ES of G1 were larger those of GO respectively. BS （ r = 0. 192, P = 0. 000） and ES （ r = 0. 249, P = 0. 000） were correlated with the IMT of carotid artery. Conclusions Ultrafast imaging technique can quickly measure the carotid artery PWV. BS and ES of carotid artery can be quick, convenient, safe,noninvasive parameters for evaluating carotid atherosclerosis.

关 键 词：弹性成像技术 颈动脉 脉搏波传导速度 颈动脉内膜中膜厚度 极速成像技术 

分 类 号：R816.2[医药卫生—放射医学]