血管回声追踪技术评价高尿酸血症患者颈总动脉弹性功能的应用价值  

Quantitative evaluation of carotid elasticity in patients with hyperuricemia by echo-tracking technology

作　　者：赵文[1] 闫志梅[1] 张桂俊[1] 王正滨[1] 丁兆艳[1] 李云萍[1] 

机构地区：[1]青岛大学医学院附属医院青岛西海岸医疗中心超声诊断科,266555

出　　处：《中华超声影像学杂志》2014年第3期211-213,共3页Chinese Journal of Ultrasonography

基　　金：青岛经济技术开发区重点科技发展计划项目（2012-2-64）

摘　　要：目的探讨血管回声追踪（echo—tracking，ET）技术检测高尿酸血症患者颈总动脉弹性功能改变的价值。方法应用ET技术对60例正常对照者、60例单纯高尿酸血症患者（A组）、60例高尿酸合并高脂血症患者（B组）颈总动脉进行检测，获得僵硬度指数（β）、血管压力一应变弹性系数（Ep）、顺应性（AC）、扩张指数（AI）及脉搏波传导速度（PWVβ）等参数，对所得数据进行统计分析。结果与对照组比较，A组及B组患者β、Ep、PWVp、AI均明显增高（P〈0．05），AC则明显减低（P〈0．05）；与A组比较，B组患者p、Ep、PwVp、AI均明显增高，AC则明显降低（P〈0．05）。结论ET技术能较早发现高尿酸血症及高尿酸合并高血脂患者颈总动脉弹性改变，为临床早期诊断与治疗动脉粥样硬化性病变提供重要依据。Objective To investigate the clinical value of echo-tracking（ET） technique in evaluating the carotid elasticity in patients with hyperuricemia and hyperuricemia combined with hyperlipidemia. Methods One hundred and twenty patients with hyperuricemia were divided into two group： group of hyperuricemia （group A） and group of hyperuricemia combined with hyperlipidemia （group B）. Sixty normal persons were served as the control group. ET was used to measure the carotid artery elastic modulus including stiffness parameters （ β）, pressure-strain elastic modulus （ Ep）, arterial compliance （ AC）, augmentation index （AI） and pulse wave conducting velocity （PWVβ）. Then the statistical data were analyzed to observe the changes of each parameter. Results In the comparison of three groups, elastic function index β,Ep,PWVβ and AI in group A and group B were higher than those of control group （ P〈 0.05） ;however,AC was lower than that of control group （P 〈0.05）. Compared with group A, elastic function index β,Ep,PWVβ,AI was higher in group B,while the AC was lower than that of group B （ P〈0.05）. Conclusions ET may be helpful to prevent atherosclerotic changes and to provide the basis for the clinical diagonosis and treatment atherosclerotic changes.

关 键 词：超声检查 高尿酸血症 颈动脉 弹性 回声跟踪 

分 类 号：R445.1[医药卫生—影像医学与核医学] R589.7[医药卫生—诊断学]