超声二维应变成像评价2型糖尿病患者颈动脉弹性  

Evaluation of the carotid artery elasticity in patients with type 2 diabetes mellitus using two-dimensional strain imaging

作　　者：李秀云[1] 邹春鹏[1] 姜淑英[1] 何慧疗[1] 寇红菊[1] 张其敏[1] 赵雅萍[1] 

机构地区：[1]温州医科大学附属第二医院超声科,325027

出　　处：《中华超声影像学杂志》2014年第3期214-217,共4页Chinese Journal of Ultrasonography

摘　　要：目的应用超声二维应变成像检测2型糖尿病患者颈动脉整体圆周应变（CS）、应变率（CSr）和硬度参数（B），探讨其评价颈动脉弹性的临床应用价值。方法选择2型糖尿病患者60例为病例组，并分为颈动脉内中膜厚度（CIMT）增厚组（34例，1．0mm〈CIMT≤1．2ram）和斑块组（26例，CIMT〉1．2mm），33例正常人为对照组。在颈总动脉二维短轴图像测量收缩期峰值CS和CSr，根据超声二维应变计算动脉硬度参数p，并将p和CS分别与CIMT进行相关性分析。结果CIMT增厚组与斑块组Cs和CSr均低于对照组（P〈0．01），斑块组CS和CSr低于CIMT增厚组（P〈0．05）；CIMT增厚组与斑块组B高于对照组（P〈0．01）；斑块组8高于CIMT增厚组（P〈0．01）；CS与CIMT显著相关（r=-0．79，P〈0．01），B与CIMT显著相关（r=0．72，P〈0．01）。结论超声二维应变成像能更早地检测出2型糖尿病患者颈动脉受累的信息，2型糖尿病患者颈动脉的变形程度随CIMT增厚而减低，硬度随CIMT增厚而增大。Objective Three parameters include circumferential strain （CS）, circumferential strain rate （CSr） and stiffness parameter （β） were measured to evaluate the elasticity of carotid artery using two- dimensional（2D） strain imaging and evaluate its clinical value in patients with type 2 diabetes mellitus （T2DM）. Methods 60 patients with T2DM were collected and divided into carotid intima-midia thickness （CIMT） thickeness group（34 cases, 1.0 mm〈CIMT≤1.2 mm） and plaque group（26 case, CIMT〉 1.2 mm）. 33 normal people were supplied as control group. The systolic global peak CS and CSr of the carotid artery were obtained from short-axis view of the common carotid artery and the stiffness parameters β was measured using 2D strain imaging. All the parameters were compared among the three groups. Results The CS and CSr were decreased and β was increased in patients with T2DM （ P 〈 0.01）, The CS and CSr obtained from the plaque group were less than that of the CIMT thickeness group（ P 〈0.05） ,but the β was higher than that of the CIMT thickeness group （ P 〈0.01）. The CS and β were correlated significantly with CIMT respectively （ r = - 0.79, P 〈 0.01 ; r = 0.72, P 〈 0.01 ）. Conclusions 2D strain imaging is a technique for early assessing the carotid artery elasticity in patients with T2DM, the thicker the CIMT is, the smaller the deformation is and the larger the β is.

关 键 词：超声检查 糖尿病 2型 颈动脉 弹性 二维应变成像 

分 类 号：R445.1[医药卫生—影像医学与核医学] R587.1[医药卫生—诊断学]