糖尿病肾病的内源性保护因素研究进展  

The research progress of endogenous renal protective factors for diabetic nephropathy

作　　者：崔焕焕[1,2] 李艳玲[1,2] 王坚[1,2] 

机构地区：[1]南方医科大学南京临床医学院 [2]南京军区南京总医院内分泌科,210002

出　　处：《中华临床医师杂志（电子版）》2013年第24期277-279,共3页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：糖尿病肾病是糖尿病最严重的并发症之一。目前有关糖尿病肾病的内源性保护因素的研究很少,但越来越多的研究结果显示,多种内源性保护因素如胰岛素、血红素加氧酶-1、VEGF-A、胰升糖素样肽-1、DPP-4抑制剂、活化蛋白C等对糖尿病肾病的发展具有保护作用。本文就目前有关糖尿病肾病的内源性保护因素的研究进展进行综述。Diabetic nephropathy （DN） is one of the most serious complications of diabetes meUitus. At present, there are few studies related with endogenous renal protective factors. However, more and more studies show that, a variety of endogenous renal protective factors such as insulin, heine oxygenase-1 （HO-1）, vascular endothelial growth factor （VEGF）-A, Glucagon like peptide-1 （GLP-1）, DPP-4 inhibitors and Activated protein C （APC）, can prevent the progress of DN. This article will review the research progress of endogenous renal protective factors for DN.

关 键 词：糖尿病肾病 内源性 保护因素 

分 类 号：R587.2[医药卫生—内分泌]