急性期间日疟患者血浆γ-干扰素和白细胞介素-17水平分析  

The plasma levels of interferon-gamma and interleukin-17 of the acute stage in patients infected with Plasmodium vivax

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作  者:孔评石[1,2] 陶志勇[1] 陶莉[1] 方强[1] 夏惠[1] 

机构地区:[1]蚌埠医学院病原生物学教研室,安徽蚌埠233030 [2]江苏省第二中医院检验科,江苏南京210017

出  处:《蚌埠医学院学报》2014年第3期295-297,共3页Journal of Bengbu Medical College

基  金:安徽省教育厅自然科学研究重点资助项目(KJ2012A200)

摘  要:目的:分析急性期间日疟患者血浆中γ-干扰素(IFN-γ)和白细胞介素-17(IL-17)水平。方法:用酶联免疫吸附方法检测19名急性期间日疟患者(间日疟组)和20名健康志愿者(对照组)血浆中IFN-γ、IL-17水平。结果:间日疟组患者血浆中IFN-γ和IL-17水平分别为(18.86±6.77)pg/ml和(41.46±21.03)pg/ml,均明显高于对照组的(9.99±8.78)pg/ml和(25.23±11.83)pg/ml(P<0.01)。结论:间日疟患者血浆中IFN-γ和IL-17的水平均升高。Objective :To investigate the plasma levels of interferon-gamma(IFN-γ) and interleukin-17 (IL-17) of the acute stage in patients infected with Plasmodium vivax. Methods:The plasma levels of IFN-γ and IL-17 in 19 patients infected with Plasmodium vivax (Plasmodium vivax group) in acute stage and 20 healthy people( control group) were measured using enzyme-linked immunosorbent assay. Results:The plasma levels of IFN-γ and IL-17 in Plasmodium vivax group( 18.86 ± 6.77) pg/ml and(41.46 ±21.03 ) pg/ml were significantly higher than those in control group (9.99 ± 8.78 ) pg/ml and ( 25.23 ± 11.83 ) pg/ml ( P 〈 0. O1 ). Conclusions : The plasma levels of IFN-γ and IL-17 of patients infected with Plasmodium vivax were increased.

关 键 词:间日疟 Γ-干扰素 白介素-17 

分 类 号:R531.3[医药卫生—内科学]

 

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