瞬时受体电位香草酸亚型1对血压的调控和靶器官的保护作用  

Regulation of Transient Receptor Potential Vanilloid Type 1 in Blood Pressure and Protection of Target Organs

作　　者：姜伶利 黄玮[1] 

机构地区：[1]重庆医科大学附属第一医院心血管内科,重庆400016

出　　处：《心血管病学进展》2014年第2期216-219,共4页Advances in Cardiovascular Diseases

基　　金：国家自然科学基金(30971212);重庆市自然科学基金计划项目CSTC(2009BB5069);重庆市卫生局课题(X1250)

摘　　要：高血压是心血管疾病的重要危险因素之一,但目前导致高血压的具体机制尚未完全阐明。近年来越来越多的研究发现感觉神经对血压具有调控作用,而该作用需依赖表达于感觉神经的瞬时受体电位香草酸亚型1。现主要研究瞬时受体电位香草酸亚型1对血压的调控及其对靶器官的保护作用。Hypertension is a key factor of cardiovascular diseases, but the mechanisms involved in essential hypertension are unknown. However, recent evidence indicates that the afferent nervous system has a role in the control of blood pressure. Transient receptor potential vanilloid type 1 expressed in an afferent nerve can regulate blood pressure and act as a sensor and regulator in cardiovascular disease. This review examines the regulation of transient receptor potential vanilloid type 1 in blood pressure and the protection of the target organs.

关 键 词：瞬时受体电位香草酸亚型1 血压 靶器官保护 

分 类 号：R544.1[医药卫生—心血管疾病]