中国老年期痴呆患病率Meta分析  

Prevalence of dementia among Chinese people aged 60 years and over:a meta-analysis

作　　者：董永海[1] 毛向群[1] 刘磊[1] 何维[1] 刘芸[2] 

机构地区：[1]江西省疾病预防控制中心业务管理科, 南昌 330029 [2]江西省人民医院干部神经内科

出　　处：《中国公共卫生》2014年第4期512-515,共4页Chinese Journal of Public Health

摘　　要：目的 采用Meta分析评价2000—2012年中国≥60岁老年人群痴呆患病率状况。方法 系统检索PubMed、Springer Link、中国期刊全文数据库、万方数据资源系统、维普中文科技期刊全文数据库中有关老年人群痴呆患病率的研究文献，采用Meta分析合并患病率，并对性别、年龄、地区、居住地、文化程度、婚姻状况、痴呆亚型等分类指标进行亚组分析。结果 共筛选出参考文献19篇，总调查人数56 988人，患者3 176例；经Meta分析，老年期痴呆患病率为4.8%（95%CI=3.7%~6.0%）；亚组分析结果显示，老年期痴呆患病率女性（6.1%）高于男性（4.1%），年龄越大者患病率越高，文盲人群患病率（7.5%）高于非文盲人群（4.1%），在婚人群患病率（4.5%）低于非在婚（8.2%），阿尔兹海默病患病率（3.3%）高于血管性痴呆患病率（0.9%）。结论 中国≥60岁人群老年期痴呆患病严重，应引起公众的普遍重视。Objective To estimate the prevalence of dementia in the elderly aged 60 years and over in China between 2000 and 2012 using meta-analysis.Methods Publications between 2000 and 2012 were extracted from PubMed,Springer Link,China National Knowledge Infrastructure（CNKI）,Wanfang Databases and Chinese Science and Technology Journal Databases（VIP）.Observational studies on prevalence of dementia were included.The prevalence of dementia was combined by meta-analysis.Subgroup analysis was undertook by gender,age,region,marital status and dementia subtypes.Results A total of 19 papers were included in this study.The total number of participants investigated was 56 988,with 3 176 dementia cases identified.The prevalence of senile dementia in the elderly was 4.8%;the women had a higher prevalence（6.1%）than the men（4.1%）;and the prevalence was significant increased with the age.The dementia prevalence in the illiterate population was 7.5%,higher than 4.1% in the literate population.The prevalence of dementia in the people married was 4.5%,lower than in the people unmarried（8.2%）.The major subtypes of dementia in the elderly were Alzheimer＇s disease（AD）and vascular dementia（VD）,with the prevalences of 3.3% and 0.9%.Conclusion Dementia among the population aged 60 years and over in China is prevalent,and attention should be paid to the prevalence among the public.

关 键 词：老年期痴呆 老年人 患病率 META分析 

分 类 号：R195.4[医药卫生—卫生统计学]