口服α1一受体阻滞剂防治肛肠病术后尿潴留的疗效分析  

Analysis on the Efficacy of Oral Aministration of al-Receptor Blocker for Prevention ＆ Treatment of Postop- erative Uroschesis of Anorectal Disease

作　　者：徐永强[1] 邓兵[1] 

机构地区：[1]四川省宜宾市第二人民医院肛肠外科,四川宜宾644000

出　　处：《中国肛肠病杂志》2014年第2期64-66,共3页Chinese Journal of Coloproctology

摘　　要：为探讨口服α1一受体阻滞剂防治肛肠病术后尿潴留的临床疗效，回顾于我科行手术治疗的340例肛肠病患者资料，根据术后是否应用α1一受体阻滞剂分为两组，其中应用α卜受体阻滞剂的设为试验组（哈乐，口服，0．2rαg／次，每天1次，230例），未应用α1一受体阻滞剂的设为对照组[110例）。对比两组患者术后尿潴留发生率、首次排尿时间；发生尿潴留后，两组患者均接受导尿处理，试验组男性患者继续服用α1一受体阻滞剂，对比观察两组男性患者导尿时的疼痛程度、尿道黏膜损伤情况及留置导尿管后下尿路的刺激症状。结果显示，试验组术后尿潴留发生率明显低于对照组，P〈O．05；术后首次排尿时间明显短于对照组，P〈O．05。试验组发生尿潴留的男性患者导尿时的疼痛程度明显轻于对照组，P〈O．05；尿道黏膜损伤率及留置导尿管后下尿路的刺激症状发生率明显低于对照组，P〈O．05。结果表明，口服α1一受体阻滞剂可有效降低肛肠病术后尿潴留的发生率，接受导尿处理的男性患者口服α1阻滞剂可缓解置导尿管时的不适，减少留置导尿管所引起的下尿路刺激症状，具有较高的临床应用价值。In order to investigate the clinical effect of oral admmtstratlon oi az-recepwx uw t, tion treatment of postoperative uroschesis of anorectal diseases,authors retropectively analyzed the data of 340 patients with anorectal diseases who had received surgery in author＇s department, according to whether administration of this blocker divided them into two groups,i, e trial group（230 eases administered this blocker, Hoola, 0.2mg/time, ltime/d） and control group （110 cases, without administration）, and com- pared incidence of uroschesis,the time of first urination between both groups;when uroschesis occured the male patients of trial group continuously administered this blocker, at this time both groups all received catheterization management the pain degree, ureter mucosa injury ratio during catheterization, and the stimulated symptoms of lower urinary tract following indwelling catheter were observed and compared be- tween both groups. As results, the uroschesis incidence, the time at the first urination after operation of tri- al group was significantly lower,shorter than that of control group（ P %0.05） win trial group the male with postoperative urosehesis suffered from significantly lighter pain during catheterization compared with con- trol group（ P %0.05） ,and their ureter mucosa injury ratio and stimulated symptoms of lower urinary tract following indwelling catheter also were significantly lower than control group（ P %0.05）. It is concluded that oral administering al-receptor blocker can effectively reduce postoperative uroschesis incidencecontin- uously orally administrating this blocker can make the received catherterization management male patient＇s uncomfortable feeling to be relieved, and stimulated symptoms of lower urinary tract follwing indwelling catherter to be reduced,in a word,above therapy has higher clinical application value.

关 键 词：Α1-受体阻滞剂 肛肠病 手术 尿潴留 防治 

分 类 号：R694.55[医药卫生—泌尿科学]