平阳霉素治疗小儿皮肤海绵状血管瘤277例临床观察  

Clinical effect of bleomycin of 277 children with cutaneous cavernous hemangioma

作　　者：赵志刚[1] 彭亮[1] 李亚军[1] 吴晓杰[1] 廉英[1] 孟丹[1] 司丽霞[1] 赵岩灵 李长越[1] 

机构地区：[1]解放军第210医院核医学科,辽宁大连116021

出　　处：《临床军医杂志》2014年第3期276-277,280,共3页Clinical Journal of Medical Officers

摘　　要：目的观察平阳霉素治疗小儿皮肤海绵状血管瘤的疗效。方法选择2006年5月—2013年4月收治的小儿皮肤海绵状血管瘤患者277例,采用平阳霉素注射治疗,根据患儿血管瘤体积注射平阳霉素,剂量为1 mg/cm3,每次注射量不超过8 mg。按照治愈、显效、好转、无效评价疗效。结果治愈率92.1%,显效率4.3%,好转率3.6%,有效率96.4%,无一例患儿发生过敏性休克。结论采用平阳霉素注射治疗小儿皮肤海绵状血管瘤安全、有效,与放射性核素32P胶体注射治疗有效率相近,且避免了32P胶体注射治疗的缺点。平阳霉素中未加利多卡因,可防止利多卡因导致的过敏性休克。Objective To observe the clinical effect of bleomycin on cutaneous cavernous hemangioma in children. Methods Methods The clinical data of 277 children ill with cutaneous cavernous hemangioma from May 2006 to April 2013 were collected. All the patients were treated with injection of bleomycin. The therapeutic dose was based on the volume of hemangioma and the maximum was 8 mg per injection. Curative effect was evaluated as healed, effective, improved and ineffective. Results The rates of healing, effectiveness and improvement were 92.1% , 4.3% and 3.6% , respectively. The overall efficiency （ rate of healing and effectiveness） was 96.4%. No children suffered from anaphylactic shock. Conclusion As a treatment for children skin cav- ernous hemangioma, bleomycin injection is safe and effective. Its effect is equal to radionuclide 32p colloid injection. However, ble- omycin injection helps to avoid some shortcomings of radiotherapy. That no lidocaine is added to bleomycin may prevent anaphylac- tic shock.

关 键 词：平阳霉素 皮肤 海绵状血管瘤 

分 类 号：R817.8[医药卫生—影像医学与核医学]