尿淀粉酶检测对急性胰腺炎临床诊断的意义  

Clinical Significance of UAMY Detection on the Diagnosis of Acute Pancreatitis

作　　者：朱敏[1] 袁昌琼[1] 杨慧英[1] 腾菲[1] 郭晓东[2] 李明阳[3] 

机构地区：[1]解放军总医院南楼消化科,北京100853 [2]解放军第302医院,北京100039 [3]解放军总医院消化内镜诊疗科,北京100853

出　　处：《现代生物医学进展》2014年第10期1904-1906,共3页Progress in Modern Biomedicine

基　　金：解放军总医院临床科研扶持基金(2012FC-TSYS-3011);国家自然科学基金青年科学基金项目(30901795)

摘　　要：目的:探讨尿淀粉酶检测结果对急性胰腺炎临床诊断的意义。方法:选取2011年6月至2012年7月在我院接受治疗的急性胰腺炎患者50例定义为AP组,选取非胰腺炎急腹症患者50例定义为NP组,选取健康人群50例定义为HS组。分别检测三组患者的血淀粉酶(SAMY),尿淀粉酶(UAMY),尿肌酐(UCR)及尿淀粉酶与尿肌酐的比值(UACR),整理并分析检测结果。结果:急性胰腺炎组和非胰腺炎急腹症组的患者的血淀粉酶、尿淀粉酶、尿淀粉酶与尿肌酐的比值均高于健康对照组,组间比较差异显著(P<0.05);非胰腺炎急腹症组与健康对照组的尿淀粉酶和尿肌酐比值相比差异不明显(P>0.05)。急性胰腺炎组的淀粉酶和尿肌酐比值的敏感性为93.41%,特异性为93%;血清淀粉酶的敏感性为86.7%,特异性为92.2%,均高于临床诊断指标的常用值。结论:急性胰腺炎尿液与尿肌酐比值的测定是早前急性胰腺炎诊断和治疗的重要检测指标。Objective： To explore the clinical significance of UAMY detective results for the diagnosis of acute pancreatitis. Methods： FiRy patients with acute pancreatitis who were treated in our hospital from June 2011 to July 2012 were selected as the AP group; Fifty patients with other abdominal diseases were chosen to be the NP group; and another fifty healthy people were defined as the HS group. Then the detective results of SAMY, UAMY, UCR and UACR of patients were detected and compared respectively. Results： The results of AP group and NP group were higher than those of the HS group, and there was statistically significant difference between two groups （P〈0.05）; There was no statistically significant difference between NP group and the HS group on the results of UAM~ and UACR （P〉0.05）. The sensitivity of UAMY and UACR was 93.41%, the specificity was 93%; The sensitivity of SAMY was 86.7%, the specificity was 92.2%. The sensitivity and specificity of UAMY and UACR in the AP group were significantly higher than the standard for diagnosing. Conclusion： It is suggested that the detection of SAMY, UAMY, UCR and UACR could be the essential indicators on the diagnosis and treatment of the acute pancreatitis.

关 键 词：急性胰腺炎 尿淀粉酶 尿肌酐 尿淀粉酶和尿肌酐比值 

分 类 号：R657.51[医药卫生—外科学]