咪唑基取代β-环糊精聚合物固相萃取剂制备及分析应用  

Preparation of Imidazolyl Substituted β-Cyclodextrin Polymers as a Solid-phase Extractant and Its Analytical Application

作　　者：周楠[1] 朱霞石[1] 

机构地区：[1]扬州大学化学化工学院,扬州225002

出　　处：《应用化学》2014年第4期474-481,共8页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金资助项目(20875082;21155001)~~

摘　　要：合成了单-6-脱氧-6-咪唑-β-环糊精聚合物（β-CDIMCP），建立了以β-CDIMCP为固相萃取剂分离分析碱性桃红T的新方法。结果表明，与β-环糊精聚合物（β-CDCP）相比，β-CDIMCP具有更好的吸附能力。室温下、pH=11.0时，β-CDIMCP能快速定量吸附碱性桃红T（吸附率95％）；以3.0mL无水乙醇在8min内可脱附碱性桃红T（脱附率90.0％）。在最佳条件下，β-CDIMCP对碱性桃红T富集倍数为10，检出限为4.9 μg／L，相对标准偏差3.4％（n=3，P=3.00mg／L），线性范围为0.09～6.00mg／L，相关系数R为0.9972。通过包合常数测定探讨了β-CDIMCP对碱性桃红T的吸附机理。采用该方法对实际样品中碱性桃红T含量测定，结果令人满意。Mono-6-deoxygi-imidazole-β-cyclodextrin polymer（β-CDIMCP） was synthesized and used as a new solid phase adsorbent to pre-eoncentrate/separate trace amount of safranine T in solutions. The results from UV-visible spectroscopy measurements show that β-CDIMCP had a better adsorption performance than β-CDCP. Safranine T was adsorbed by β-CDIMCP rapidly with an adsorption efficiency of 95% at room temperature and pH = 11.0. When 3.0 mL of anhydrous ethanol was used as the eluant, the elution efficiency reached 90% in 8 minutes. Under the optimum condition, the preconcentration factor of the proposed method was 10. The detection limit（ DL）, RSD, linear range, and correlation coefficient was found to be 4.9 μg/L, 3.4% （ n = 3, p = 3.00 mg/L） , 0.09 ～ 6.0 mg/L and 0.9972, respectively. This proposed method was successfully applied to the determination of safranine T in real samples. The molecular interaction between β-CDIMCP and safranine T was studied through the inclusion constant study.

关 键 词：碱性桃红T 咪唑-β-环糊精聚合物 固相萃取 紫外可见光谱法 

分 类 号：O657.7[理学—分析化学]