兔不同死因死后脑组织CT影像学变化的时间规律性研究  

Time regularity of brain computed tomography images changes after different causes of death in rabbits

作　　者：李晓娜[1] 郑吉龙[2] 单迪[2] 纪伟[1] 

机构地区：[1]中国医科大学基础医学院化学教研室,沈阳110001 [2]中国刑事警察学院法医系法医病理教研室,沈阳110035

出　　处：《解剖科学进展》2014年第2期145-150,共6页Progress of Anatomical Sciences

基　　金：沈阳市科技计划项目(No.F13-182-9-00)

摘　　要：目的研究兔不同死因死后129h内脑组织CT影像学的变化规律与死亡时间的关系。方法分别采用机械性窒息、失血性休克和空气栓塞法,建立家兔死亡模型;在不同死后间隔时间对家兔进行颅脑薄层螺旋CT扫描,结合专业的计算机图像分析技术,监测脑组织面积/颅腔面积比、脑组织平均CT值、颅腔整体平均CT值等参数变化,并作统计学分析。结果脑组织平均CT值随着死亡时间的延长,呈先升高后降低。死后27h内,脑组织面积/颅腔面积比基本无变化;死后33h,脑组织面积/颅腔面积比、颅腔整体平均CT值随着死后间隔时间延长逐渐下降。建立了体现各项参数变化趋势的二项式回归方程(p<0.001),具有显著的统计学意义。结论采用现代放射CT影像技术获得的不同死因死后颅脑组织的多参数的非线性回归方程,为法医学推断死亡时间提供了客观、准确的方法和参考依据。Objective To investigate the time regularity of brain computed tomography images changes after different causes of death in rabbits. Methods Different death models were established by mechanical suffocation, hemorrhagic shock and air embolism respectively. CT scaning was performed to investigate the postmortem cerebral changes after death. Brain area/cranial cavity area ratio, the average CT value of brain tissue and average cranial CT value of the overall were determined and analyzed statistically. Results The average CT value of brain tissue was iirst increased and then decreased with the extension of postmortem intervals, but with almost no changes for the ratio of brain area/cranial area within 27h postmortem. Brain area/cranial cavity, average cranial CT value of the overall decreased 33h postmortem with the extension of postmortem intervals. The regression equations were established successfully to reflect change trends. Conclusion Multi- parameter nonlinear regression equations obtained by modern CT imaging techniques would provide an objective and accurate method for estimation of postmortem interval.

关 键 词：死亡时间 脑 CT 免 

分 类 号：DF795.4[医药卫生—法医学]