树状聚合物功能化碳纳米管/钯纳米复合物的制备及其非酶葡萄糖传感应用  

Preparation of dendrimer funcationalized carbon nanotube / Pd nanoparticles composite for nonenzymatic glucose biosensing

作　　者：侯代红 赖国松[1] 张海丽[1] 

机构地区：[1]湖北师范学院化学化工学院,湖北黄石435002

出　　处：《湖北师范学院学报（自然科学版）》2014年第1期37-41,共5页Journal of Hubei Normal University(Natural Science)

基　　金：湖北省教育厅重点项目(D2010250);国家自然科学基金(21075030)

摘　　要：将树状聚合物(PAMAM)通过共价反应嫁接在羧基化碳纳米管(CNTs)表面后用于钯纳米粒子(Pd NPs)的原位沉积,制备成CNTs-PAMAM/Pd NPs复合物。通过壳聚糖包埋将制备的该钯纳米复合物用于玻碳电极的修饰,并通过交流阻抗法和循环伏安法对电极性能进行表征和优化,制备成可用于葡萄糖的安培检测的非酶电化学传感器。实验表明,在最佳实验条件下该传感器可在较短时间内(<3 s)实现对葡萄糖的快速稳态安培响应,并可在从0.03 mmol/L至61.7 mmol/L较宽线性范围内实现对葡萄糖的准确测定,检出限为11.5μmol/L。该传感器成本低廉,性质稳定,且具有较好的选择性和重复性,因而在实际应用中具有较好的发展前景。Polyamidoamine （PAMAM） dendrimer was covalently grafted with carboxylated carbon nanotubes （CNTs） for the in situ deposition of palladium nanoparticles （Pd NPs）.Based on the electrode modification with the as -prepared CNTs-PAM-AM/Pd NPs nanocomposites and the further coating of chitosan on its surface , a nonenzymatic amperometric glucose biosensor was developed.Electrochemical impedance spectroscopy and cyclic voltammetry were used to characterize and optimize the performance of the sensor.Under the optimal conditions, this sensor exhibited a rapid amperometric response towards glucose （less than 3 s）, and a wide linear range from 0.03 to 61.7 m mol· L^-1 was obtained with a detection limit of 11.5μmol·L^-1 （S/N=3）.This biosensor has low cost , good stability, selectivity and repeatability, thus indicating great potentials for practical applications.

关 键 词：非酶传感器 葡萄糖 化学修饰电极 碳纳米管 钯纳米粒子 

分 类 号：O167.3[理学—数学]