从草酸青霉菌中分离得到的立体异构体Hydroxyscytalone的光谱学研究  

Stereochemistry of Hydroxyscytalone Isolated from Penicillium Oxalicum Using VCD,ECD and OR Methods

作　　者：纪彦南 何平[1] 李金亮[1] 郭秀杰[1] 王香粉 俞和[1] 申世刚[1] 朱华结[1] 

机构地区：[1]河北大学中国手性中心,化学与环境科学学院,药物化学与分子诊断教育部重点实验室,保定071002

出　　处：《高等学校化学学报》2014年第4期746-749,共4页Chemical Journal of Chinese Universities

基　　金：河北大学人才引进项目资助~~

摘　　要：从真菌草酸青霉菌(Penicillium oxalicum)中分离得到一个新的立体异构体Hydroxyscytalone,其平面结构采用核磁共振和高分辨质谱等进行确定,其立体化学通过振动圆二色光谱、电子圆二色光谱和旋光光谱进行证实.A new stereoisomer of hydroxyscytalone from Penicillium oxalicum was obtained. Its planar struc-ture was established using 1 H NMR, 13 C NMR and high resolution MS. In its stereochemistry study, the very recently developed method, vibrational circular dichroism（ VCD） was used. The calculation is relatively sim-ple by computing the corresponding characteristics based on ground state of electronics. By comparison of com-puted VCD, ECD and OR with the experimental data, stereochemistry can be well studied.

关 键 词：Hydroxyscytalone 草酸青霉菌 振动圆二色光谱 电子圆二色光谱 旋光 

分 类 号：O629.9[理学—有机化学]