血压晨峰现象对老年原发性高血压患者认知功能的影响  

Effects of morning blood pressure surge on cognitive function in the elderly patients with essential hypertension

作　　者：周英智[1] 马丽娜[1] 冯明[1] 李耘[1] 钱玉英[1] 

机构地区：[1]首都医科大学宣武医院综合科,北京市100053

出　　处：《实用老年医学》2014年第3期201-203,共3页Practical Geriatrics

基　　金：卫生部公益性行业科研专项基金(201002011);北京市卫生局保健课题项目(京13-02)

摘　　要：目的探讨血压晨峰现象(morning blood pressure surge,MBPS)对老年原发性高血压认知功能的影响。方法对107例老年原发性高血压患者进行动态血压的监测,分为MBPS组(40例)和无MBPS(NMBPS)组(67例),检查所有患者空腹血脂、血糖和肌酐,并进行问卷调查及简短精神状态量表(MMSE)的测定。结果 MBPS组的收缩压高于NMBPS组(P<0.05)。MBPS组的MMSE评分显著低于NMBPS组(P<0.01)。结论老年原发性高血压有MBPS者更易发生认知功能障碍。Objective To explore the effects of morning blood pressure surge （MBPS） on cognitive function in the elderly patients with essential hypertension. Methods 107 patients receiving the detection of 24h ambulatory blood pres- sure monitoring were divided into MBPS group （n = 40） and non-MBPS （NMBPS） group（ n = 67）. The levels of blood li- pids, glucose and creatinine were determined, and MMSE was measured. Results The level of systolic blood pressure in MBPS group was higher than that in NMBPS group（P〈0. 05）. The score of MMSE in MBPS group was lower than that in NMBPS group（P〈0. 01 ）. Conclusions MBPS is closely related with the cognitive impairment in the elderly patients with essential hypertension.

关 键 词：高血压 晨峰现象 认知功能 老年人 

分 类 号：R544.1[医药卫生—心血管疾病]