76例强直性脊柱炎患者人类白细胞抗原B27检测结果分析  

作　　者：谭春萍[1] 

机构地区：[1]攀枝花市第二人民医院,617000

出　　处：《内蒙古中医药》2014年第4期83-84,共2页Inner Mongolia Journal of Traditional Chinese Medicine

摘　　要：目的:探讨人类白细胞抗原B27(human leukocyte anti-gen B27,HLA-B27)在强直性脊柱炎(Ankylosing spondylitis,AS)诊断及鉴别诊断中的临床价值。方法:2012年03月-2013年06月来本院就诊的76例As患者进行HLA-B27抗原检测,并与同期45例背腰腿疼痛患者以及50例健康体检者HLA-B27抗原检测结果作对比。结果:AS患者、背腰腿疼痛患者、健康体检者3组人群HLA-B27阳性率分别为92.1%、6.7%及2.0%,AS患者组HLA-B27阳性率明显高于背腰腿疼痛患者和健康体检者,差异有统计学意义(P<0.05)。结论:HLA-B27检测对AS的早期诊断、鉴别诊断、治疗及预后评估均具有重要意义。Objective ： To investigate the effect of human leukocyteantigen B27 （ human leukocyte anti - gen B27, HLA - B27 ） in patients with ankylosing spondylitis （ Ankylosing spondylitis, AS） clinicalvalue in diagnosis and differential diagnosis of. Methods： a retrospective analysis of 2012 03 months - 2013 years 06 monthsin our hospital 76 cases of As patients with HLA - B27 antigen detection results, and compared with 45 cases of dorsal lumbar and leg pain patients and 50 healthy subjects were analyzedresults of detecting HLA - B27 antigen. Results： the patients with AS, back, lumbar and leg pain patients with healthy subjects with positive rate of 3 groups of HLA - 1327 were 92. 1%, 6. 7% and 2% ,the positive rate of AS group was significantly higher than that in patients with HLA - B27 back waist and leg pain and healthy controls, the difference was statistically significant （ P 〈 0. 05 ）. Conclusion： the diagnosis, differential diagnosis, treatment and evaluation of prognosis of early HLA - B27 detection of AS has very important significance.

关 键 词：人类白细胞抗原B27 强直性脊柱炎 流式细胞分析 

分 类 号：R593.23[医药卫生—内科学] R446.6[医药卫生—临床医学]