天山花楸正丁醇部位降糖效果研究  

Hypoglycemic Effect of n-butanol Part of Sorbus tianschanica

作　　者：李乐[1] 苏向辉[2] 唐辉[1] 

机构地区：[1]石河子大学药学院,新疆石河子832002 [2]石河子大学第一附属医院,新疆石河子832002

出　　处：《安徽农业科学》2014年第8期2303-2304,共2页Journal of Anhui Agricultural Sciences

基　　金：国家自然科学基金项目(81260627);新疆兵团重点领域科技攻关(2013BA034);石河子大学优秀青年科技人才培育计划立项项目(2012ZRKXYQ21)

摘　　要：[目的]对天山花楸的有效成分进行提取分离,探索正丁醇部位的降糖效果。[方法]采用回流提取法对天山花楸进行提取,梯度洗脱,获得正丁醇部位,以链脲佐菌素(STZ)诱发小白鼠糖尿病模型,利用该部位进行降血糖试验。[结果]正丁醇部位给药组与模型组相比,有明显降糖效果。[结论]天山花楸具有一定的抗糖尿病作用。[ Objective ] To study the hypoglycemic effect of n-butanol part of tianschaniea. [ Method ] Sorbus tianshanica was extracted with flux method, through gradient elution, n-butanol part was obtained. The diabetic rat model was induced by intraperitoneal injection of ST-Z, the rat blood glucose levels was detected. [ Result ] n-butanol part could lower blood glucose level in STZ induced hyperglycaemic rats. [ Conclusion ] Sorbus tianschanica has significant hypoglycemic effect.

关 键 词：天山花楸(Sorbus tianschanica Rupr) 正丁醇部位 糖尿病 

分 类 号：S567[农业科学—中草药栽培]