桃仁提取物对大鼠实验性矽肺纤维化的影响  

The Study of Effects of Semen Persicae Extract on Silicotic Fibrosis in Rats

作　　者：洪长福[1] 娄金萍[1] 周华仕[1] 何令媛[1] 朱丽秋[1] 

机构地区：[1]浙江省医学科学院,杭州310013

出　　处：《劳动医学》2000年第4期218-219,共2页

摘　　要：[目的 ]探讨桃仁提取物 (苦杏仁甙 )抗矽肺纤维化作用。 [方法 ]采用桃仁提取物治疗矽肺大鼠 ,观察矽肺胶原蛋白和生化指标变化 ,及对大鼠矽肺病理影响。 [结果 ]桃仁提取物能显著抑制矽肺大鼠胶原蛋白合成和减少血清铜蓝蛋白。 [结论Objective] This study is to study the anti fibrotic effects of semen persicae extract(amygdalin)in rats.[Methods] Silicotic rats were treated with semen persicae extract to study the changes of silicotic collagen,biochemical indices and effects on pathology of silicotic rats.[Results] Semen persicae extract significantly restrained synthesis of collagen and reduced ceruloplasmin in serum of silicotic rats.[Conclusion] Semen persicae extract inhibited remarkably silicotic fibrosis in rats.

关 键 词：桃仁提取物 矽肺纤维化 胶原蛋白 

分 类 号：R135.2[医药卫生—劳动卫生]