N-马来酰化壳聚糖及其配合物的合成与表征  

Synthesis and characterization of N-maleoyl chitosan and its complexes

作　　者：容学德[1] 

机构地区：[1]广西民族大学预科教育学院,广西南宁530008

出　　处：《化工进展》2014年第4期1006-1009,共4页Chemical Industry and Engineering Progress

摘　　要：碱性条件下将壳聚糖脱晶,利用红外光谱(FT-IR)对其结构进行了确证,并以N,N-二甲基甲酰胺和无水乙醇为介质,将脱晶壳聚糖与马来酸酐在室温条件下摩尔比按1∶1进行酰化反应18 h,合成了取代度DS=63%的N-马来酰化壳聚糖。由FT-IR测试的结果表明了马来酸酐成功接到壳聚糖分子的氨基上。将制备的N-马来酰化壳聚糖在室温下分别与氯化锌、氯化铜反应6 h,制得N-马来酰化壳聚糖与二价锌离子和二价铜离子的配合物。采用FT-IR及电子顺磁共振光谱(EPR)对配合物的结构进行表征。结果表明,N-马来酰化壳聚糖在温和条件下能与Cu(Ⅱ)、Zn(Ⅱ)形成配位化合物,N-马来酰化壳聚糖中的氨基与羧基共同参与配位。The decrystal chitosan was achieved by treating the chitosan raw material in alkaline solution. Its structure was confirmed by the Fourier transform infrared spectra （FT-IR）. The N-maleoyl chitosan （CTM） was synthesized in N,N-dimethyl formamide （DMF） and anhydrous ethanol （EtOH） solution through acylation reaction between the maleic anhydride and decrystal chitosan by the mole ratio of 1 ： 1 for 18 hours at room temperature. The substitution degree of obtained N-maleoyl chitosan was 63%. The FT-IR spectrum shows that the maleic anhydride is successfully grafted onto the --NHe of chitosan. The N-maleoyl chitosan further reacted with copper chloride and zinc chloride for 6 hours at room temperature to provide the metal complexes CTMCu and CTMZn, respectively. The structures of N-maleoyl chitosan and its complexes were investigated by FT-IR and electron paramagnetic resonance （EPR） spectra. The results show that the N-maleoyl chitosan can react with Cu（ II ） and Zn（ II ） ions in mild condition. And the carboxylate and amino groups chelate the metal center.

关 键 词：N-马来酰化壳聚糖 反应 配合物 合成 表征 

分 类 号：O636[理学—高分子化学]