嗜酸粒细胞性支气管炎患者呼出气一氧化氮变化检测  

The change detection of eosinophilic bronchitis patient nitric oxide

作　　者：丁巍[1] 邬超[1] 王文艺[1] 杨晓红[1] 

机构地区：[1]新疆维吾尔自治区人民医院呼吸与危重症医学科,830001

出　　处：《临床合理用药杂志》2014年第10期15-16,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨嗜酸粒细胞性支气管炎(EB)患者呼出气一氧化氮(FENO)的变化特点。方法选择30例EB患者(未经激素治疗)、激素治疗3个月后的EB患者30例和正常对照60例。检测呼出气一氧化氮,对比3组FENO水平。结果 EB患者FENO水平为(40.78±4.71)PPb显著高于正常对照组(16.15±1.70)PPb和激素治疗3个月后的FENO值(18.20±1.56)PPb,差异均有统计学意义(P<0.05)。但激素治疗3个月后EB患者的FENO水平与对照组比较差异无统计学意义(P>0.05)。结论 EB患者通过检测FENO可提高诊断准确率,且可诊断EB及治疗和作为病情监测指标之一。Objective To study the characteristic of hange eosinophilic bronchitis patient nitric oxide. Methods Se- lected 30 cases patients with eosinophilic bronchitis without hormone therapy, Selected 30 cases patients with eosinophilic bron- chitis with Hormone therapy, Selected 60 cases patients normal control population. All involved in the trial were examined nitric oxide. After examined, compared the level of nitric oxide of 3 groups. Results The level of FENO of EB （40.78±4.71 ） was higher than that of control group（ 16.15 ± 1.70） and hormone therapy（ 18.20 ±1.56）, the difference was statistically signifi- cant（ P 〈 0. 05 ）. There was no statistically significant between hormone therapy and control group（ P 〉 0.05 ）. Conclusion The diagnostic accuracy of eosinophilic bronchial can be enhanced by examined nitric oxide, can enhance the diagnosis and treatment of eosinophilic bronchial, to be one of monitoring indicators.

关 键 词：嗜酸性支气管炎 呼出气一氧化氮 诊断 

分 类 号：R562.21[医药卫生—呼吸系统]