卡前列素氨丁三醇注射液联合缩宫素预防产后出血的疗效观察  

The clinical effect observation of carboprost tromethamine injection combined with oxytocin in preventing postpartum hemorrhage

作　　者：周宝芹[1] 渠玉雪 

机构地区：[1]苏州工业园区跨塘医院妇产科,江苏省苏州市215122

出　　处：《临床合理用药杂志》2014年第10期31-32,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的观察卡前列素氨丁三醇注射液联合缩宫素预防产后出血的临床效果。方法将50例宫缩乏力性产后出血高危因素产妇随机分为观察组和对照组各25例。观察组胎儿娩出后予缩宫素20U宫体注射,卡前列素氨丁三醇注射液0.25mg肌内注射。对照组予缩宫素20U宫体注射,缩宫素20U静脉滴注。应用称重法计算2组产后2h及24h出血量、出血率和不良反应。结果观察组产后2h及24h出血量明显少于对照组,差异均有统计学意义(P<0.05)。观察组产后出血率为16.0%(4/25)低于对照组的56.0%(14/25),差异均有统计学意义(P<0.05)。结论卡前列素氨丁三醇注射液联合缩宫素治疗宫缩乏力性产后出血较单独使用缩宫素疗效显著,具有临床意义。Objective To observe the clinical efficacy of carboprost tromethamine injection combined with oxytocin in preventing postpartum hemorrhage. Methods 50 cases of cesarean section uterine atony postpartum hemorrhage risk factors of maternal, were randomly divided into observation group and control group, each of 25cases. After give birth, observation group was treated by oxytocin 20U palace injection, carboprost tromethamine injection 0.25mg intramuscular injection. Control group was treated by oxytocin 20U palace injection, oxytocin 20U intravenous infusion. After treatment, compared the postpartum hem- orrhage volume, bleeding rate and the adverse reactions of 2 groups. Results The bleeding volume of observation,2h,24h after give birth, was higher than that of control group, the difference was statistically significant （ P 〈 0.05 ）. The rate of postpartum hemorrhage of observation group was 16.0% was lower than that of control group 56.0%, the difference was statistically signif- icant（P 〈0.05）. Conclusion Carboprost tromethamine injection combined with oxytocin in preventing＇ postpartum hemor- rhage has a good efficacy, worthy of clinical application.

关 键 词：卡前列素氨丁三醇注射液 预防 产后出血 宫缩乏力 

分 类 号：R714.461[医药卫生—妇产科学]