广州市番禺区农民急性冠心病事件发病率及20年变化趋势  

Prevalence of acute coronary heart disease among farmers in Panyu, Guangzhou： a 20-year population-based study

作　　者：邓木兰[1] 李河 石美玲[1] 何永全 廖剑勇 杨捷 江夏杏[1] 郭成业[1] 麦劲壮[1] 

机构地区：[1]广东省心血管病研究所广东省人民医院心外科流行病学研究室广东省医学科学院,广州510080 [2]广州市番禺区大石人民医院社区管理科 [3]广州市番禺区钟村医院防保科 [4]广州市南沙区中医院防保科

出　　处：《中华心血管病杂志》2014年第3期236-240,共5页Chinese Journal of Cardiology

基　　金：＂八五＂国家重点科技攻关项目（85-915-01-01）;＂九五＂国家重点科技攻关项目（96-906-02-01）

摘　　要：目的 监测广州市番禺区全年龄组农民急性冠心病事件的发病水平及长期变化趋势,为疾病防治提供依据.方法 1991至2001年、2010至2011年在广州市番禺区对中美心肺疾病流行病学合作研究的监测人群进行监测.采用世界标准人口进行标化,按年度、性别、年龄分别计算急性冠心病事件发病粗率和年龄标化率；比较该人群在2个不同时期冠心病事件的发病特点；采用回归分析法计算急性冠心病事件发病率的年均变化率,并进行统计学分析.结果 1991至2001年,番禺区女性农民急性冠心病事件发病率呈上升趋势（P＜0.05）.番禺区农民急性冠心病事件年龄标化发病率2010至2011年为28.50/10万（粗率为34.06/10万）,1991至2001年为15.57/10万（粗率为16.14/10万）,标化率增长了83.04％.男性发病高峰年龄在75～ 79岁,女性在80～84岁.男性发病率增长幅度最大的是35～39岁年龄段,其次是75～ 79岁年龄段；女性发病率增长幅度最大的是50～ 54岁年龄段,其次是65～ 69岁年龄段.2010至2011年75岁及以上患者占全部发病人数的47.37％（36/76）,较1991至2001年（33.73％,56/166）增长了40.44％.结论 广州市番禺区农民急性冠心病事件的发病率处于国内中等偏低水平,20年来呈平缓上升趋势；番禺区的冠心病防治应针对发病率增幅较大的特定年龄人群.Objective To monitor the incidence change of acute coronary heart events in the all- ages farmers in Panyu District, Guangzhou City during 1991--2001 and 2010--2011. Methods The surveillance on the same defined population as that from the PRC-USA cooperative epidemiologic project on the cardiovascular and pulmonary diseases 30-year ago was carried out in Panyu, Guangzhou in 1991--2001 and 2010--2011. The crude incidence of acute coronary events and the age-standardized incidence rate were calculated by the year, gender and age, and standardized with the world standard population age distribution. Incidences at the two different periods were compared. The annual average changing rate of the incidence was obtained by the regression analysis methods. Results In the 11 consecutive years of 1991-- 2001, a upward trend on the incidence of acute coronary events among the farmers in women in Panyu District was found （P 〈 0. 05 ）. The incidence of the acute coronary events in the year of 2010--2011 was significantly higher than that in the year of 1991 to 2001 [ 34. 06 per 100 000 （ age-adjusted rate as 28.50 per 100 000） versus 16. 14 per 100 000 （age-adjusted rate as 16.57 per 100 000）, P〈0.05]. The age- adjusted rate increased by 83.04%. Peak incidence of acute coronary events in males was noticed in 75 - 79 age group, and in 80 - 84 age group in females. Comparing to the period of 1991--2001, the largest incidence increases appeared in the age groups of 35 - 39 and 75 - 79 years in males, while in the age groups of 50 - 54 and 65 - 69 years in females. Up to 47. 37% （36/76） events occurred on the age group older than 75 years, raised by 40.44% comparing to that in 1991--2001 （33.73%, 56/166）. Conclusions The incidence of acute coronary events among farmers in Panyu District is at middle or low level of China but there is an increasing trend in acute coronary incidence from 1991 to 2011. Our results suggest that the prevention and treatment on acute coronary syndrome should be strengthened, and

关 键 词：冠状动脉疾病 发病率 

分 类 号：R541.4[医药卫生—心血管疾病]