七种染料对鲤鱼肝微粒体芳烃羟化酶的诱导  

THE INDUCTION OF ARYL HYDROCARBONHYDROXYLASE (AHH) OF CARP (CYPRINUS CARPIO)LIVER MICROSOME BY SEVEN DYES

作　　者：徐楠[1] 王春霞[1] 莫争[1] 呼世斌[2] 

机构地区：[1]中国科学院生态环境研究中心环境水化学国家重点实验室,北京100085 [2]西北农林科技大学基础科学系,杨凌712100

出　　处：《环境化学》2001年第1期23-26,共4页Environmental Chemistry

基　　金：国家自然科学基金(29637010和3977152)资助项目

摘　　要：以鲤鱼肝微粒体为实验体系,研究了七种染料化合物对其芳烃羟化酶(ＡＨＨ)的诱导,发现七种染料都可以诱导ＡＨＨ的活性,随染料浓度增大ＡＨＨ的活性升高．七种染料对ＡＨＨ活性诱导能力大小为:酸性红Ｂ＞派拉丁蓝ＲＲＮ＞普拉红Ｂ＞活性艳红Ｋ－２ＢＰ＞活性艳红Ｋ－２Ｇ,媒介大红Ｓ－８０＞分散红Ｅ－４Ｂ,与其毒性大小相关．The aryl hydrocarbon hydroxylase (AHH) activity of carp ( Cyprinus Carpio) .liver microsome induced by seven dyes was examined. The all tested dyes induced AHH activity to different extent. The AHH activity increased according to the increase of the dye concentration. The intense of AHH activity induced by seven dyes was as following order; acid red B > acid complex blue RRN > weak acid brilliant red B > reactive brilliant red K-2BP > reactive brilliant red K-2G, acid mordant red S-80 > disperse red E-4B. The intense of AHH activity was related to the toxicity of the chemicals.

关 键 词：芳烃羟化酶 染料 鲤鱼 诱导 肝微粒体 芳烃羟化酶 生物监测 

分 类 号：X503[环境科学与工程—环境工程]