婴儿牛奶蛋白过敏45例临床分析  

Clinical analysis of 45 cases of cow's milk protein allergy in infants

作　　者：魏菊荣[1] 罗宏英[1] 周少明[1] 

机构地区：[1]深圳市儿童医院,广东深圳518026

出　　处：《中国实用儿科杂志》2014年第4期300-302,共3页Chinese Journal of Practical Pediatrics

摘　　要：目的分析婴儿牛奶蛋白过敏的临床特征，以提高对婴儿牛奶蛋白过敏的，临床诊治水平。方法回顾性总结2012年1月至2012年11月深圳市儿童医院通过饮食回避诊治的45例1—6个月牛奶蛋白过敏患儿的临床资料。结果病程2周至5个月不等，临床表现为慢性腹泻伴或不伴便血、呕吐、拒奶、肠绞痛、腹胀等，部分伴有湿疹，病程长的患儿伴有不同程度的营养不良。45例均给予游离氨基酸粉或深度水解蛋白配方粉喂养及对症处理后临床症状缓解，继续喂养营养状况改善。结论牛奶蛋白过敏临床表现多样化，易误诊，饮食回避是主要的诊断和治疗方法且疗效肯定。Objective To analyze the clinical characteristics of infants with cow＇ s milk protein allergy （CMPA） and to raise awareness of diagnosis and treatment. Methods Totally 45 cases were diagnosed with cow＇ s milk protein allergy by cow＇s milk protein elimination in 2012 in Shenzhen Children＇s Hospital, and the clinical data were analyzed retrospectively. Results The course of disease ranged from 2 weeks to 5 months. The main clinical manifestations were chronic diarrhoea, with or without bloody stool, vomiting, food refusal, colic, and bloating, some accompanied by eczema and longer duration in ehildren.with varying degrees of malnutrition. Amino acid formula or extensively hydrolyzed protein formula feeding and symptomatic treatment improved the symptoms in all 45 cases, and feeding continued to im- prove the nutritional status. Conclusion Cow＇ s milk protein allergy has nonspecific clinical manifestations and the diagnosis is difficult. Food avoidance is the main method of diagnosis and treatment.

关 键 词：牛奶蛋白过敏 游离氨基酸粉 深度水解蛋白配方粉 婴儿 

分 类 号：R72[医药卫生—儿科]