影响胃癌根治术患者预后的相关因素分析  

Factors influencing Prognosic of patients undergoing radical gastrectomy

作　　者：严建宇[1] 杨钦清[1] 朱建民[1] 陈伦牮 尤丽吐孜 

机构地区：[1]武警新疆总队医院军人病区,乌鲁木齐830091 [2]新疆自治区人民医院普二科,乌鲁木齐830001

出　　处：《武警医学》2014年第3期267-268,271,共3页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的探讨影响胃癌根治术患者预后的相关因素。方法调查在我院行胃癌根治术60例患者,采集资料包括性别、年龄、TNM分期、肿瘤大小、组织分化、手术方式、远处转移、复发情况等。结果全组患者术后复发和(或)转移30例,占50%。其中腹膜转移5例,骨转移1例,盆腔转移2例,卵巢转移2例,肺转移4例,肝转移6例;局部复发10例。组织分化程度、TNM分期及肿瘤大小为影响胃癌根治术患者预后的相关因素(P<0.05);其中组织学分型、TNM分期是影响胃癌根治术患者预后的独立危险因素(P<0.05)。结论 TNM分期、组织分化程度是影响胃癌根治术患者预后的独立危险因素,提高术后生存率的关键是综合防治措施。Objective To investigate the factors influencing prognostic of patients undergoing gastrectomy. Methods From January 2009 to January 2010 in this hospital,60 patients received radical gastrectomy. Their clinical data, including gender, age, TNM stage, tumor size, histological grade, surgical approach, distant metastasis, and recurrence, were collected. Results Of all 60 apatients,30 had recurrence and /or metastasis, accounting for 50%. Peritoneal metastasis occurred in 5 cases, bone metastasis in 1 case, pelvic metastases in two cases, ovarian metastasis in 2 cases, lung metastasis in four cases, and liver metastases in six cases. Local recurrence in 10 cases. Histological grade, TNM stage, and tumor size were prognostic factors affecting gastric cancer patients （P〈0.05）. Cox regression analysis found that the histological type and TNM stage were independent prognostic factors affecting patients with radical gastrectomy （P〈0.05）. Conclusion The key to improving the survival rate of patients with gastric cancer lies in comprehensive prevention and control measures to reduce the morbidity and mortality of patients with gastric cancer.

关 键 词：胃癌根治术 预后 相关因素 

分 类 号：R656.6[医药卫生—外科学]