美国野水鸭Ⅰ型副黏病毒病HI免疫抗体消长规律试验  

Variation of HI immune antibodyto paramyxovirus typeⅠin American wild water duck

作　　者：曾强[1] 张济培[1] 张福英[1] 刘佑明[1] 林镇城 张方愉[1] 邱明贤[1] 

机构地区：[1]佛山科学技术学院动物医学系,广东佛山528231 [2]狮山镇农林服务管理中心,广东佛山528234

出　　处：《佛山科学技术学院学报（自然科学版）》2014年第2期51-54,共4页Journal of Foshan University(Natural Science Edition)

基　　金：佛山市科技局科技发展专项资金项目(2009032)

摘　　要：试验采用鸭副黏病毒GSFY株（A苗）、GSBY株（E苗）油乳剂灭活疫苗和鸡新城疫NH株（N苗）油乳剂灭活疫苗对7d、14d和21d的美国野水鸭分别进行不同剂量和不同次数的免疫，检测各实验组鸭的HI抗体变化情况。结果显示，美国野水鸭分别免疫后，HI抗体A苗21d和E苗14d时分别达4．55log和5．27log以上，维持时间为35～42d以上。N苗除3次免疫组21d时达到4．0log以上维持时间21～28d外，1次和2次免疫组均不能达到4．0log的抗体水平。结果表明，对美国野水鸭作I型副黏病毒病灭活疫苗免疫具有良好的免疫效果，尤以3次免疫为佳．3个不同来源毒株的灭活疫苗以GSBY株油乳剂灭活疫苗的免疫效果最好。Oil adjuvant inactivated ,,occines of Duck Paramyxovirus （GSFY strain from Muscovy Duck and GSBY strain from Cherry Valley Duck）and Chicken Newcastle Disease （NH strain） were inoculated to 7 d, 14 d, 21 d American wild water ducks at different doses and times. The variation of HI antibody were investigated in all the ducks. The results were： HI antibody A and E of American wild water duck was over 4.55 log and 5.27 log at 21 d and 14 d after inoculation respectively and the level maintained over 35 ~ 42 d. HI antibody N arrived at 4. 0 log at 21 d after inoculation and maintained till 21-28 d for the group inoculated for 3 times, it did not arrive at the level of 4.0 log for the groups inoculated for only 1 time or 2 times. The results showed that the inactivated vaccines of Duck Paramyxovirus had good immune effects, especially for 3 times inoculation. The GSBYstrain of oil adjuvant inactivated vaccines had the best immune effects among the 3 strains.

关 键 词：美国野水鸭 鸭副黏病毒 免疫 HI抗体 

分 类 号：S858.32[农业科学—临床兽医学]