严重脓毒症血制品应用和免疫支持治疗  

Application of blood products and immunological support therapy for severe sepsis

作　　者：张晨美[1] 宁铂涛[1] 

机构地区：[1]浙江大学医学院附属儿童医院PICU,杭州310003

出　　处：《中国小儿急救医学》2014年第4期208-211,共4页Chinese Pediatric Emergency Medicine

基　　金：国家自然科学基金项目（81270045）;浙江省科技重大专项（2012C13024-3）

摘　　要：严重脓毒症和脓毒性休克是在脓毒症基础上并发器官功能衰竭或者组织灌注不足为特征的临床综合征,其病死率高.虽然早期足量快速的液体复苏是严重脓毒症和脓毒性休克治疗的关键,但白蛋白、血浆、红细胞、血小板、丙种球蛋白等血制品输注,以及血液净化、乌司他丁联合胸腺肽和抗CD14单克隆抗体等免疫支持也起着一定作用.Severe sepsis and septic shock is a clinical syndrome with sequential organ dysfunction or tissue hypoperfusion induce by sepsis. Although early, adequately and rapidly initial resuscitation plays pivotal role in the management, but infusion of albumin, plasma, red blood cell, platelet, gamma globulin and other blood products and the immunological support with ulinastatin combined with thymosin, blood purification and anti CD14 monoclonal antibody therapy also play an important role.

关 键 词：脓毒症 血制品 免疫支持 

分 类 号：R459.7[医药卫生—急诊医学]