不同产地五味子类药材质量特征分析  

Quality Assessment on Schisandrae Fructus from Different Habitats

作　　者：秦亚东[1] 王义祁[1] 汪荣斌[1,2] 王存琴[3] 刘晓龙[1,2] 周宙[1] 

机构地区：[1]安徽中医药高等专科学校,安徽芜湖241002 [2]安徽中药资源研究所,安徽芜湖241317 [3]中国药科大学,江苏南京211198

出　　处：《中药材》2014年第2期210-214,共5页Journal of Chinese Medicinal Materials

基　　金：安徽芜湖市科技计划2009年度重点科技项目医药(7-2)

摘　　要：目的:同时测定不同产地五味子类药材中5种主要木脂素类成分的含量,并对其质量特征进行分析。方法:采用HPLC法同时测定不同产地五味子类药材中五味子醇甲、五味子醇乙、五味子酯甲、五味子甲素、五味子乙素含量。以5种成分含量为指标,使用SPSS 19.0、SOLO软件对30批样品进行主成分分析、聚类分析。结果:30批样品被分为三大类,反映不同产地五味子类药材的内在质量特征。结论:主成分分析、聚类分析方法可为五味子类药材分类、质量评价提供依据,为节约药材资源及合理用药提供借鉴和参考。Objective：To assay five lignans in Schisandrae Fructus collected from different habitats. Methods：HPLC method wasdeveloped to assay Schizandrol A, Schizandrol B, Schisantherain A, deoxyschizandrin and y-schizandrin in Schisandrae Fruetus. Hierar- chical clustering analysis （HCA） and principal components analysis （PCA） were performed to evaluate and classify 30 batches of sam- pies based on the contents of the five lignans using SOLO and SPSS 19.0 software. Resuhs：30 batches of samples were divided into three groups,which reflecting their quality characteristics. Conclusion：PCA and HCA provide the basis for the classification and quality evaluation of Schisandrae Fructus. The content analysis provides reference for resources saving and rational using of Schisandrae Fructus.

关 键 词：五味子类药材 质量特征 主成分分析 聚类分析 

分 类 号：R282.6[医药卫生—中药学]