卡前列素氨丁三醇联合益母草注射液防治高危产妇剖宫产出血的临床研究  

Clinical study of carboprost tromethamine combined with motherwort injection in prevention of high-risk ce-sarean section hemorrhage

作　　者：丁霄雁 冯涛[1] 耿慧[1] 刘芳[1] 马爱荣[1] 

机构地区：[1]淄博市中心医院产科, 山东省淄博255036

出　　处：《中国基层医药》2014年第7期1006-1007,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的：探讨卡前列素氨丁三醇联合益母草注射液防治高危产妇剖宫产出血的效果。方法选择120例行剖宫产手术并有潜在出血征兆产妇为研究对象，采用数字表法随机分为两组，观察组60例采用卡前列素氨丁三醇联合益母草注射液进行预防治疗，对照组60例采用缩宫素进行预防治疗，比较两组防治效果。结果治疗后观察组产后2 h、24 h出血量分别为（422．41＆#177;213．49） mL、（35．29＆#177;16．44） mL，均明显少于对照组的（589．64＆#177;345．21）mL、（69．31＆#177;29．47）mL（t＝6．732、8．915，均P＜0．05）；观察组无1例发生产后出血，对照组发生产后出血5例，两组差异有统计学意义（χ2＝4．973，P＜0．05）。结论卡前列素氨丁三醇联合益母草注射液防治高危产妇剖宫产出血具有显著的效果，可减少剖宫产子宫出血的发生并减少出血量，促进子宫复旧，有利于产妇的康复。Objective To investigate the carboprost ammonia butyl alcohol three plus motherwort injection on prevention of high risk maternal postpartum hemorrhage effect .Methods 120 cases of cesarean section operation and potential bleeding symptom of women were selected as the research object ,and randomly divided into two groups , the observation group of 60 cases using carboprost ammonia butyl alcohol three joint of leonurus heterophyllus injec -tion for prevention and treatment ,the control group of 60 cases used oxytocin for prevention and treatment ,prevention and treatment effects were compared between the two groups .Results After treatment,the observation group 2h,24h postpartum hemorrhage were （422.41 ＆#177;213.49）mL,（35.29 ＆#177;16.44）mL,were significantly less than those in the control group （589.64 ＆#177;345.21）mL,（69.31 ＆#177;29.47）mL（t=6.732,8.915,all P＆lt;0.05）;the observation group 1 cases without production after bleeding ,control group 5 cases of postpartum hemorrhage ,statistically significant differ-ences between the two groups （χ2 =4.973,P＆lt;0.05）.Conclusion Carboprost ammonia butyl alcohol three plus motherwort injection on prevention of high risk maternal postpartum hemorrhage has a significant effect ,which can re-duce the cesarean section uterine bleeding and reduce the amount of bleeding ,promote uterine involution ,conducive to maternal rehabilitation .

关 键 词：卡前列素氨丁三醇 益母草注射液 剖宫产术 产后出血 

分 类 号：R714.461[医药卫生—妇产科学]