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作 者:王明辉[1] 张艳华[1] 赵明月[1] 方玉[1] 张文思[1]
机构地区:[1]北京大学肿瘤医院暨北京市肿瘤防治研究所,恶性肿瘤发病机制及转化研究教育部重点实验室药剂科
出 处:《肠外与肠内营养》2014年第2期94-97,共4页Parenteral & Enteral Nutrition
摘 要:目的:了解肿瘤专科医院肝肾功能异常病人全肠外营养(TPN)医嘱应用情况,为临床安全合理用药提供参考。方法:采用回顾性调研方法,抽取肿瘤医院静脉药物调配中心配制的200例肝肾功能异常病人TPN医嘱1 428组。结果:目前肿瘤医院TPN医嘱的糖脂比、热氮比、阳离子用量等合理率>97%。临床医师注重医嘱中特殊营养素的添加。肝功能异常的病人,TPN医嘱中应用中/长链脂肪乳的比例为26.95%,肝病用复方氨基酸的比例为2.01%,肾功能异常病人应用肾病用复方氨基酸的比例为0.02%。结论:对肝功能异常病人应用TPN时可适当选择复方氨基酸和中/长链脂肪乳,肾功能异常病人适当选用复方氨基酸,以减轻肝肾负担,有利于病人的预后。Objective : To analyze the medical orders for total parenteral nutrition in liver dysfunc- tion or kidney dysfunction cancer patients. Methods: The retrospective investigation was made, and the 1 428 groups of TPN orders were analysed. Results: The TPN orders had basically rational in the cancer hospital and the rational rate was more than 97 %. In the patients of liver dysfunction, the use of medium/long chain fat emulsion was up to 26.95%, and the compound amino acid of hepatopathy was 2.01%. In the patients of kidneys dysfunction, the compound amino acid of nephropathy was 0.02%. Conclusion: In the patients of liver dysfunction, the medium/long chain fat emulsion and compound amino acids of hepatopathy should be used, and in the patients of kidneys dysfunction, the compound amino acid of nephropathy should be used.
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