东菱迪芙治疗难治性中重度突发性聋疗效观察  

Observation on the effect of Batroxobin on refractory moderate and severe sudden deafness

作　　者：刘苏辐[1] 李健东[1] 汪学勇[1] 赵亮[1] 姬巍[1] 白娟[1] 魏伯俊[1] 

机构地区：[1]首都医科大学附属北京世纪坛医院耳鼻咽喉头颈外科,北京100038

出　　处：《中华耳科学杂志》2014年第1期103-105,共3页Chinese Journal of Otology

摘　　要：目的探讨难治性突聋新的治疗方法。方法回顾性分析44例难治性突聋的临床资料,其中男性24例、女性20例,年龄33岁--68岁,平均47岁,病程2周--2个月。所有病例均在院外做过常规扩血管、营养神经治疗,个别做过高压氧、针灸、理疗等综合治疗,恢复不佳或无恢复。入院后均给予东凌迪芙溶栓治疗一个疗程,并监测纤维蛋白原指标。结果所有44例病人中有34例听力均有明显好转,大部分得到较好的恢复或全部恢复,有效率77.3%。结论对突聋患者行常规方法治疗2周,无效时可结合东凌迪芙溶栓治疗,能有效的改善病人症状恢复听力。Objectives To report an innovative method in treating refractory sudden deafness. Methods Clinical data of 44 cases of refractory sudden deafness were studied retrospectively. The patients included 24 males and 20 females, aged 47 years on average （33 to 68 years）, and the disease duration ranged from 2 weeks to 2 months. All cases had undergone and failed the routine vasodilation and neurotrophic therapies, and even unconventional therapies including high-pressure oxygen, acupuncture and physical therapy in a few cases. Batroxobin antithrombosis was provided as one course of treatment, and plas- ma fibrinogen was monitored. Results Significant improvement of heating occurred in 34 of the 44 cases （77.3%）. Conclu- sions Batroxobin antithrombotic therapy seems to be an effective rescue treatment for cases of sudden deafness that have failed the 2 weeks routine treatments, with significant heating benefits.

关 键 词：东凌迪芙 突发性聋 常规治疗 溶栓治疗 新型治疗方法 

分 类 号：R764.437[医药卫生—耳鼻咽喉科]