猪圆环病毒2型疫苗研究进展  

Research Progress on Porcine Circovirus Type 2 Vaccine

作　　者：王宪文[1] 

机构地区：[1]河南科技学院动物科学学院,河南新乡453003

出　　处：《中国畜牧兽医》2014年第4期252-255,共4页China Animal Husbandry & Veterinary Medicine

基　　金：河南省教育厅自然科学研究项目(2009A230002)

摘　　要：猪圆环病毒2型(PCV2)有多个免疫学和毒力上重要的抗原表位,这些表位为疫苗和诊断制剂的设计提供了理论依据。近年来PCV2弱毒疫苗、灭活疫苗、亚单位疫苗、活载体疫苗和DNA疫苗等多种疫苗已取得新的研究进展和实际应用,且PCV2疫苗在种猪和仔猪中的应用效果良好。此外,羧甲基新茯苓多糖、谷氨酸、精氨酸和硒等免疫增强剂及营养物质均有助于提高PCV2感染动物的机体免疫力。为更好地防控猪圆环病毒病,作者对PCV2疫苗相关研究进行综述。There are many epitopes that are important in immunology and virulence on the surface of porcine circovirus type 2 （PCV2）, which offer insights for the direction of future research. Great development has been produced in the study on PCV2 vaccines, several efficacious vaccines have already been produced. Nutritive substance such as carboxymethylpachymaran, L-glutamine, arginine supplementation and Selenium can improve the preventive or curative effect in animals infected with PCV2. Research progress on PCV2 vaccine was introduced for better control of PCV2-associated diseases.

关 键 词：猪圆环病毒2型 表位 疫苗 

分 类 号：S852.5[农业科学—基础兽医学]