中药提取新技术及其在国内的转化应用研究  

Research status and translational application of new extraction techniques of traditional Chinese medicine

作　　者：王赛君[1] 伍振峰[1,2] 杨明[1,2] 王雅琪[1] 王芳[1,2] 柯刚[1] 黄居敏[1] 

机构地区：[1]江西中医药大学现代中药制剂教育部重点实验室,江西南昌330004 [2]成都中医药大学,四川成都610075

出　　处：《中国中药杂志》2014年第8期1360-1367,共8页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(81173565);江西省教育厅项目(GJJ13603)

摘　　要：提取是中药制药过程的关键环节,直接影响着药品的质量,提取新技术的发展是中药制造工业技术转型升级的关键,关系着中药现代化的进程。该文首先简述了国内研究报道较多的超声提取法、微波提取法、超临界流体萃取、半仿生提取法、酶法提取、动态逆流提取、减压沸腾提取等提取新技术的基本原理、特点与发展现状。在提取新技术的转化应用方面,统计分析国家自然科学基金委员会对提取新技术的资助情况及其研究成果概况,国家知识产权局上公布的提取新技术的专利,综合分析五大制药机械行业网站上提取新技术相关设备的供应情况。结果表明,当前的提取新技术在中药行业内还存在基础研究薄弱、转化困难、基础研究与应用脱节的问题,探讨加速基础研究转化可能的途径与方法,为中药提取新技术的发展提供参考。Extraction is the critical link during pharmaceutical process of traditional Chinese medicine （TCM）, which is di- rectly related to the quality of drugs. So the key to technology upgrading of pharmaceutical equipment in Chinese materia medica enter- prise is the development of new extraction techniques, which concerns the modernization of TCM. In this paper, fundamentals, traits, and development status of new extraction technologies were firstly introduced, including ultrasound extraction, microwave extraction, super fluid extraction, semi-bionic extraction method, enzymatic treatment extraction, continuous countercurrent extraction, vacuum extraction. Then information of projects supported by the National Natural Science Foundation of China was analyzed in order to recog- nize the assistance and research results of new extraction techniques. The patents authorized by the State Intellectual Property Office were also summarized for the purpose of understanding the achievement transformation. The information about extraction equipments was collected and screened to acquire the characteristics and market situation. The results showed that there are still problems about new extraction technologies, such as weak basic study, hard transformation of achievements, and the disconnection between research study and practical application. It is necessary to discuss the approaches and methods for accelerating the transformation of fundamental research, which will provide references for the long-term development of new extraction techniques of TCM.

关 键 词：提取新技术 项目资助 成果分析 转化应用 

分 类 号：R284.2[医药卫生—中药学]