SDS胶束体系中亚甲蓝与血清白蛋白的相互作用  

The Interaction of Methylene Blue and Bovine Serum Albumin in SDS Micelle System

作　　者：郭荣[1] 范国康[1] 刘天晴[1] 焦新安[2] 

机构地区：[1]扬州大学理学院化学化工系,扬州225002 [2]扬州大学生命科学与技术学院,扬州225009

出　　处：《物理化学学报》2001年第2期185-188,共4页Acta Physico-Chimica Sinica

基　　金：国家自然科学基金 !(29733110;20073038)资助项目&&

摘　　要：The interaction of methylene blue(MB) and bovine serum albumin(BSA) is investigated in the SDS micelle system which is simulated as one kind of coexisted albumin. The interaction parameters of MB and BSA and simulated albumin such as partition coefficientκ、 normal binding free energyΔ G、 average binding number n are calculated. The results show that most of MB is in the form of monomer in SDS micelle systems； the main interaction of MB and BSA is of static electric and H-bind force,and that of MB and simulated albumin is only of static electric force.The interaction of methylene blue (MB) and bovine serum albumin (BSA) is investigated in the SDS micelle system which is simulated as one kind of coexisted albumin. The interaction parameters of MB and BSA and simulated albumin such as partition coefficient kappa normal binding free energy Delta G(-) average binding number n are calculated. The results show that most of MB is in the form of monomer in SDS micelle systems; the main interaction of MB and BSA is of static electric and H-bind force, and that of MB and simulated albumin is only of static electric force.

关 键 词：亚甲蓝 牛血清白蛋白 模拟蛋白 SDS胶束 分子间相互作用 

分 类 号：O629[理学—有机化学]