应用PASS系统对我院质子泵抑制剂使用情况分析  

Analyze the use of proton pump inhibitors by using PASS

作　　者：荆俊丽[1] 张想旺[1] 马玉想[2] 马守江[1] 

机构地区：[1]中国人民解放军第107医院药剂科,山东烟台264000 [2]中国人民解放军第107医院信息科,山东烟台264000

出　　处：《药学研究》2014年第4期233-234,240,共3页Journal of Pharmaceutical Research

摘　　要：目的了解我院质子泵抑制剂(PPIs)临床用药中存在的不合理用药问题,分析不合理用药原因,并提出合理用药建议。方法利用合理用药监测系统(PASS)对我院2013年1月到8月住院患者用药医嘱进行监测,提取涉及PPIs用药医嘱并对监测结果进行分析。结果涉及PPIs用药共4 468例患者,146 374条医嘱,其中不合理用药医嘱共4 669条,不合理用药发生率为3.19%。绝对禁止黑灯医嘱0条,高度警惕红灯医嘱2 762条,一般注意黄灯医嘱1 907条,主要表现为重复治疗(34.03%)、药物相互作用(31.55%)、剂量范围(27.44%)、重复成分(6.81%)、儿童给药(0.13%)、给药途径(0.04%)。结论 PPIs在临床用药中存在部分不合理用药问题,临床药师应针对性提出合理用药建议,提高PPIs临床用药安全性。Objective To analyze the unreasonable drug use problems and reasons of proton pump inhibitors （ PPIs ） in clinical application, then put forward suggestions for rational use of PPIs. Methods The prescriptions of inpatients from January, 2013 to August in our hospital were monitored by rational drug use monitoring system（PASS）. The results involving PPIs were extracted and analyzed statistically. Results In the irrational prescriptions, there were 14 634 pieces prescrip- tions of 4 468 cases involving PPIs, of which there were 4 669 pieces unreasonable prescriptions, and the incidence of unrea- sonable drug use was 3.19%. The number of absolutely forbidden black lamp orders was 0 ,high alert red orders was 2 762 and generally attention yellow light orders was 1 907, which were mainly repeated treatment （ 34. 03% ）, drug interactions （ 31.55 % ） , dosage range （ 27.44% ） , repeated component （ 6. 81% ） , medication for children （0. 13 % ） and the route of ad- ministration（0. 04% ）. Conclusion Irrational drug use problems of PPIs were existed in clinical, so clinical pharmacists should propose advice for rational drug use to improve PPIs clinical medication safety.

关 键 词：合理用药监测系统 质子泵抑制剂 合理用药 

分 类 号：R969.3[医药卫生—药理学]