胚胎移植第5天血清P/E2与IVF/ICSI-ET妊娠结局的相关性研究  

Study of the Correlation Between Serum P/E2 and Pregnancy Outcome of IVF/ ICSI-ET on the 5th Day after Embryo Transfer

作　　者：杜婷[1] 任春娥[1] 李建娟[1] 张安清[1] 

机构地区：[1]潍坊医学院,山东潍坊261031

出　　处：《辽宁医学院学报》2014年第2期42-44,共3页Journal of Liaoning Medical University (LNMU) Bimonthly

摘　　要：目的探索在IVF/ICSI-ET中,胚胎移植第5天血清孕酮-雌激素比值对体外受精-胚胎移植妊娠结局的预测价值。方法收集接受IVF-ET长方案促排卵方案进行体外受精(IVF)/卵泡浆内单精子显微注射(ICSI)的患者移植周期资料进行分析,根据移植后妊娠结局分为妊娠组(300例,包括宫内活胎及妊娠结局不良者)及未妊娠组(380组),于移植第5天取血查血清雌二醇(E2)和孕激素(P)。结果妊娠组移植第5天的E2、P、P/E2分别为648.3±309.4、90.6±61.8、159.4±106.7,明显低于未妊娠组,P<0.05。结论移植第5天恰当的雌孕激素比例与移植的妊娠结局有关。Objective To investigate the predictive value of serum progesterone and estrogen ratio （ SP/E2 ） to pregnancy out-come of in vitro fertilization/intracytoplasmic sperm injection （IVF/ICSI-ET） on the fifth day after embryo transfer.Method By col-lecting and analyzing the transfer cycle data of patients receiving IVF-ET long protocol ovulation induction in vitro fertilization （ IVF） /intracytoplasmic sperm injection （ICSI）.According to the outcome of pregnancy after transfer, these data were divided into pregnant group （300 cases, including live intrauterine fetal and adverse pregnancy outcomes） and non pregnancy group （380 cases）.Then blood was taken and serum levels of estradiol （E2） and progesterone （P） were checked on the fifth day after transfer.Results On the fifth day of transfer, the values of E2, P, P/E2 of pregnancy group were 648.3±309.4, 90.6±61.8, 159.4±106.7, which were significantly lower than those of the non pregnant group, P〈0.05.Conclusion On the fifth day after transfer, appropriate proportion of estrogen and progesterone is associated with the pregnancy outcome of transfer.

关 键 词：胚胎移植 血清E2 孕激素 雌二醇比值 妊娠结局 SERUM E2 

分 类 号：R714.69[医药卫生—妇产科学]