陕西省HIV/AIDS患者生存时间回顾性队列研究  

Survival of HIV/AIDS Patients in Shanxi Province: a Retrospective Cohort Study

作　　者：董丽芳[1] 王敬军[1] 常文辉[1] 任强[1] 邢爱华[1] 李翔[1] 胡婷[1] 贾华[1] 

机构地区：[1]陕西省疾病预防控制中心,710054

出　　处：《中国卫生统计》2014年第2期213-216,共4页Chinese Journal of Health Statistics

摘　　要：目的描述陕西省HIV/AIDS患者生存时间的分布特征,探讨其影响因素。方法采用回顾性队列研究方法,使用寿命表描述HIV/AIDS患者的生存时间,Cox模型分析其影响因素。结果 2415例HIV血清学阳性患者经确证检测后的中位生存时间为8.61年。越早开始治疗(RR=8.08×10-11),治疗持续时间越长(RR=6.35×10-11),患者死亡危险越低。未治疗患者,确证检测年龄延迟(RR=1.04),死亡危险增加;及时检测CD4水平(RR=0.20),死亡危险降低。疾病状态进展为AIDS、文化程度低、母婴传播都是影响生存时间的危险因素。结论及时检测和尽早治疗是HIV/AIDS患者长期生存的重要保护因素,三级预防策略适用于艾滋病防治。Objective The aim of this study was to describe survival time of HIV/AIDS patients in Shaanxi Province and to ex- plore its influencing factors. Methods In this retrospective cohort study, survival time of HIV/AIDS patients was described using life ta- ble. And COX model was used to analyze influencing factors. Results 2415 cases of patients were collected with a median survivai time of 8.61 years. Early treatment（ RR = 8. 08 x 10 - 11 ） and long duration of treatment（ RR = 6. 35 x 10 - 11 ） were protective factors for survival of HIV/AIDS patients. The course of disease of AIDS, the low level of education and mother-to-child transmission are the risk factors af- fecting survival time. Conclusion HIV detected in time and early treatments are important protective factors for long-term survival of HIV/AIDS patients. Epidemiological tertiary levels of prevention strategy are more applicable to the current situation of AIDS prevention.

关 键 词：艾滋病 生存时间 队列研究 

分 类 号：R512.91[医药卫生—内科学]