草酸钙结晶-肾小管细胞损伤机制研究进展  

New progress of mechanisms of calcium oxalate crystals and renal tubular cell injury

作　　者：吴浩然[1] 胡波[1] 施国伟[1] 

机构地区：[1]复旦大学附属上海市第五人民医院泌尿外科,上海200240

出　　处：《临床泌尿外科杂志》2014年第4期365-367,共3页Journal of Clinical Urology

基　　金：上海市重点专科建设项目(编号ZK2012A22);复旦大学青年骨干基金项目(编号11L-33)

摘　　要：草酸钙是肾结石中最常见的化学成分。肾钙盐结晶是草酸钙结石形成的关键步骤之一,而近年来研究发现肾钙盐结晶形成与肾小管上皮细胞损伤密切相关。本文就草酸钙结石形成和肾小管上皮细胞损伤相互作用机制方面进行综述。Calcium oxalate is the most common chemical compound found in kidney stones. Renal calcium salt crystallization is one of the key steps in the calcium oxalate stone formation. Moreover, renal calcium salt forma- tion is found closely related to renal tubular epithelial cell damage in recent years. Here we provide a review of the mechanisms of relationship between calcium oxalate stone formation and renal tubular epithelial cell injury.

关 键 词：草酸钙 机制 肾结石 肾小管上皮细胞 

分 类 号：R692.4[医药卫生—泌尿科学]