中医药分期治疗类风湿性关节炎的药性功效初步分析  

Preliminary analysis of the property of Chinese medicine for the staged treatment of rheumatoid arthritis

作　　者：王威[1] 张田[1] 王晓霞[1] 孙文燕[1] 翟华强[1,2] 

机构地区：[1]北京中医药大学中药学院,北京100102 [2]北京师范大学资源学院资源生态与中药资源研究所,北京100875

出　　处：《中国医药导报》2014年第12期84-87,91,共5页China Medical Herald

基　　金：国家自然科学基金项目(编号81373887)

摘　　要：目的通过文献查阅及整理,分析中医药分期治疗类风湿性关节炎(RA)常用中药的药性特点和功效主治。方法借鉴循证医学的思路与方法,对RA按活动期用药和稳定期用药进行分类,以中国期刊全文数据库(CNKI)、万方、中国生物医学文献数据库(CBM)为主库,检索词为"类风湿性关节炎"、"RA"、"中医药",收集近十年中医药治疗RA临床资料。将药物进行归纳、整理,分析中药的性、味、归经、有毒无毒以及功效。结果①活动期用药特点:四气方面,温性药使用频次最高,使用频率占43.2%,其次是寒性药占30.7%,平性药占18.2%。五味方面,苦味药使用频率最高,占34.9%,其次是辛味药占30.1%,甘味药占25.7%。归经方面,归肝经最多,占23.3%,归脾经占16.8%,归肺经占13.4%,归胃经占12.4%。毒性方面,有毒中药占11.4%,无毒中药占88.6%。功效方面,祛风湿药使用频率最高,占21.5%,其次是活血化瘀药占16.8%,清热药占13.6%,补虚药占12.5%,解表药占11.4%。②稳定期用药特点:四气方面,温性药使用频次最高,占45.6%;其次是平性药占25.1%,寒性药占23.3%。五味方面,甘味药使用频率最高,占33.8%,其次是辛味药占29.5%,苦味药占25.4%。归经方面,归肝经最多,占26.1%,归脾经占15.4%,归肺经占14.8%,归肾经占13.2%。毒性方面,有毒中药占12.1%,无毒中药占87.9%。功效方面,补虚药使用频率最高,占22.7%,其次是祛风湿药占20.8%,活血化瘀药占16.1%,解表药占13.2%,清热药占10.7%。结论治疗RA活动期用药多辛温祛风湿、活血化瘀,稳定期多用甘温补益、活血,分阶段使用、分期治疗反映了中医药治疗RA的特点和优势。Objective To review and analyze the property of Chinese medicine for the staged treatment of rheumatoid arthritis, through literature review and organize. Methods Reference to the ideas and methods of evidence-based medicine, accorded to the active and stable period medication classification, the Chinese journal full text database （CNKI）, Wan Fang, Chinese biomedical literature database （CBM） as main base, searching for the word ＂RA＂, ＂ rheumatoid arthritis＂, ＂Chinese medicine＂ collects the treatment of rheumatoid arthritis clinical literature of traditional Chinese medicine in recent ten years. To analyze the flavor and channel tropism of the traditional Chinese medicine which were summarized and collated. Results By statistics： ①In the treatment of rheumatoid arthritis activity period： first, four nature statistics： warm medicine was 43.2%, which was the highest frequency of use, cold medicine was 30.7% and leveling drug was 18.2%. Second, five tastes statistics, bitter drug was 34.9%, pungent drug accounted for 30.1%, sweet medicine was 25.7%. Third, channel tropism statistics, 23.3% was owned by the liver, the spleen was 16.8%, 13.4% was owned by the lung and 12,4% was owned by the stomach. Fourth, the toxicity of statistics, toxic medicine was 11.4% and non-toxic medicine was 88.6%. Fifth, efficacy aspects, rheumatism medicine was 21.5%, the highest frequency of use, blood circulation drugs was 16.8%, and 13.6% was antipyretic, tonic medicine was 12.5%,relieving drug was 11.4%. ②In the treatment of rheuma- toid arthritis stable period： first, four nature statistics： warm medicine was 45.6%, leveling medicine was 25.1%and cold medicine was 23.3%. Second, five tastes statistics, sweet drug accounted for 33.8%, pungent drug was 29.5% and bitter medicine was 25.4%. Third, channel tropism statistics, 26.1% was owned by the liver, spleen Sutra was 15.4%, 14.8% was owned by the lung and 13.2% was owned by the kidney. Fourth, the toxicity of statistics, toxic medicine was 12.1% and

关 键 词：类风湿性关节炎 中医药 活动期 稳定期 药性 功效 

分 类 号：R593.22[医药卫生—内科学]