促进人全能干细胞自我更新的无滋养层基底材料研究进展  

Research Progress in Feeder Free Substrates for Promoting Human Pluripotent Stem Cells Self-renewal in Vitro

作　　者：郭义兵[1] 石璐[1] 王凤志[1] 张鲁杰[1] 杨宁[1] 陈莉[1] 

机构地区：[1]天津工业大学材料科学与工程学院,天津300387

出　　处：《材料导报》2014年第5期103-107,共5页Materials Reports

基　　金：国家自然科学基金(31200719;50973084)

摘　　要：综述了基质胶、细胞外基质蛋白及DNA重组蛋白涂层、多肽序列及聚合物涂层、膜材料和水凝胶等基底材料在人全能干细胞体外长期自我更新的研究进展,并指出了其中存在的问题及发展趋势。The research progress of feeder free substrates newal in vitro, including Matrigel, ECM protein coatings and quence, polymer coatings, membrane and hydrogel. In addition, are reviewed for hESC and hiPSC long-term self-re- DNA recombinant protein coatings, polypeptide se- the existing problems and the development tendencyare pointed out.

关 键 词：人全能干细胞 人诱导多能干细胞 无滋养层培养 基底材料 

分 类 号：R318.08[医药卫生—生物医学工程]