不同产地丹参药材中丹参酮ⅡA和丹酚酸B含量比较  

Comparison of the Contents of Tanshinone ⅡA and Salvianolic Acid B in Salviae Miltiorrhizae from Different Producing Areas

作　　者：陈彻[1] 王勇[1] 王晶[1] 李海龙[1] 杨雅丽[1] 王芳[1] 楚惠媛[1] 

机构地区：[1]甘肃中医学院,甘肃兰州730000

出　　处：《中医药学报》2014年第1期32-34,共3页Acta Chinese Medicine and Pharmacology

基　　金：甘肃省财政厅基本科研业务费专用资金资助(甘财政[2010]176号)

摘　　要：目的:测定和比较不同大规模栽培产地丹参药材中丹参酮ⅡA和丹酚酸B含量。方法:采用高效液相色谱法,选用Synchropak PR100-5色谱柱,检测波长分别为270nm和286nm。结果:丹参酮ⅡA和丹酚酸B含量均较高的是四川中江栽培品。山西芮城栽培品丹参酮ⅡA含量尽管最低,但丹酚酸B含量却最高。结论:丹参中丹参酮ⅡA和丹酚酸B的含量与产地关系较大,此研究结果可作为丹参药材采购及临床选用的参考依据。Objective： To determine and compare the contents of tanshinoneⅡA and salvianolic acid B in salviae miltiorrhizae from different producing areas. Methods： HPLC was employed to determine the contents of tanshinoneⅡA and salvianolic acid B. Synchropak PR100- 5 column was adopted in this process. The detective wavelength was set at 270 nm and 286nm,respectively. Results： Both of tanshinone ⅡA and salvianolic acid B levels of salviae miltiorrhizae from Sichuan Zhongjiang were higher. However,the tanshinone ⅡA level of salviae miltiorrhizae from Shanxi Ruicheng was the lowest,but salvianolic acid B level was the highest. Conclusion： The contents of tanshinoneⅡA and salvianolic acid B in salviae miltiorrhizae could be related to different producing areas. The results can be used as a reference for purchasing and using salviae miltiorrhizae in clinic.

关 键 词：丹参 丹参酮ⅡA 丹酚酸B 高效液相色谱法 产地 

分 类 号：R284.1[医药卫生—中药学]