儿童肠道病毒性脑炎234例流行病学及临床分析  

Clinical and epidemiological analysis of 234 cases of enteroviral encephalitis in children

作　　者：刘华[1] 龙振昼[1] 池宏亮[1] 陈江平[1] 李慧[1] 赵建锋[1] 刘招云 

机构地区：[1]福建医科大学附属闽东医院感染性疾病科,福建福安355000 [2]福建医科大学附属闽东医院信息科,福建福安355000

出　　处：《热带医学杂志》2014年第3期324-326,共3页Journal of Tropical Medicine

摘　　要：目的探讨肠道病毒性脑炎的流行病学及临床特征。方法对2011年5-12月期间入院的234例肠道病毒性脑炎患儿进行流行病学及临床特征分析。结果 234例肠道病毒性脑炎分布于宁德市福安市3个街道办事处、2个城郊乡镇为中心的区域,波及周边25个乡镇,流行高峰季节为5-7月份,6月龄至15岁的儿童,特别是男童比女童感染率高;临床表现以发热、头痛、呕吐为主,多数病例白细胞、C-反应蛋白升高。脑脊液细胞数正常或轻度升高、糖及氯化物正常;可伴脑电图异常;随机送检的10份脑脊液、咽拭子及粪便分离出埃可30型肠道病毒。结论该地区流行的儿童病毒性脑炎由埃可30型肠道病毒引起,其临床症状典型,经适当治疗后预后良好。Objective To investigate clinical and epidemiological features Of enteroviral encephalitis in children. Method The epidemiological and clinical data of 234 hospitalized children suffering from enteroviral encephalitis during epidemic period from May to September,2011 were analyzed and summarized. Results 234 cases of enteroviral encephalitis distribute across five populated districts of center Fu＇an city and 25 towns around it. Epidemic occurs in May to July, 2011. 6 months to 15 years old children especially male were more susceptible. Main symptoms were fever, headache, vomiting and increase of white blood cell and CRP in most parents of the patient child. The count of cell in spinal fluid was normal or increased slightly.Some cases appeared abnormal electroencephalogram. Echo 30 virus was isolated from 10 samples of spinal fluid,throat swab and faeces in CDC of Fujian province. Conclusion The viral encephalitis that epidemic in Fu＇an city and around it was caused by Echo 30 enterovirus and this disease have typical symptom and good prognosis after adequate medical treatment.

关 键 词：肠道病毒性脑炎 埃可30型肠道病毒 流行病学 l临床表现 儿童 _ 

分 类 号：R512.3[医药卫生—内科学]