紫萁贯众抗炎有效部位的研究  

Study on the Effective Component of Japanese Flowering Fern Rhizome with Anti-inflammatory Action

作　　者：穆丽莎[1] 崔文[1] 费烨[1] 付深振 王晶[1] 高增平[1] 

机构地区：[1]北京中医药大学中药学院,北京100102

出　　处：《世界中医药》2014年第3期372-373,共2页World Chinese Medicine

基　　金：北京中医药大学中药先导化合物发现与开发创新团队项目

摘　　要：目的:确定紫萁贯众抗炎作用有效部位,为进一步研究紫萁贯众抗炎作用的活性成份奠定基础。方法:通过二甲苯致小鼠耳廓肿胀实验研究紫萁贯众各极性部位的抗炎活性。结果:紫萁贯众各极性部位对二甲苯致小鼠耳肿胀的影响均具抑制作用,乙酸乙酯低剂量及正丁醇高剂量与地塞米松的抗炎效果相近。结论:中药紫萁贯众的乙酸乙酯部位和正丁醇部位为抗炎有效部位。Objective： To determine the effective component of JapaneseFloweringFernRhizome with anti-inflammatory action. Methods： Anti-inflammatory activities of the diffident parts of JapaneseFloweringFernRhizomewere studied on the swelling mice ear induced by xy- lene. Results： All the polar parts of JapaneseFloweringFernRhizome had inhibitory effects on the xylene-induced mice ear swelling. N- butyl alcohol high dose group and ethyl acetate low dose group showed the similar anti-inflammatory action to that of DXM （ Dexametha- sor）. Conclusion：Japanese Flowering Fern Rhizome has anti-inflammation effect. Ethyl acetate low dose part and N-butyl alcohol part are the effective components with anti-inflammation action.

关 键 词：紫萁贯众 抗炎 有效部位 

分 类 号：R285.6[医药卫生—中药学]