抗骨增止疼片薄膜包衣处方及工艺研究  

Film Coating Solutions of Kangguzengzhiteng Tablets

作　　者：高华娟[1] 李希[2] 黄嫣[2] 冯建安[2] 杨华[1] 李远辉[1] 

机构地区：[1]成都中医药大学药学院,四川成都610075 [2]四川省中医药科学院中医研究所,四川成都610031

出　　处：《亚太传统医药》2014年第8期21-22,共2页Asia-Pacific Traditional Medicine

摘　　要：目的:建立抗骨增止疼片薄膜包衣的处方及工艺。方法:欧巴代作成膜材料,对抗骨增止疼片进行薄膜包衣。结果:包衣后的片剂外观色泽均匀,硬度、片重差异、崩解时限等指标均符合《中华人民共和国药典》2010年版的要求,包衣后药物的引湿性有明显的改善。结论:采用欧巴代进行包衣,有效地降低了药物的吸湿性,该工艺操作简单可行,适合工业化生产。Objective：To prepare the Kangguzengzhiteng film-coating Tablets. Methods：Opadry is selected to be the film coating material in Kangguzengzhiteng Tablets. Results：The appearance, hardness, weight difference and disintegration time of the tablets were in line with the relevant requirements of pharmacopoeia of the People＇s Republic of China（2010 edition）. The hygroscopicity of the tablet was significantly decreased after film-coating. Conclusion ： The bygroscopicity of Kangguzengzbiteng film-coating Tablets is significantly decreased after film-coating with Opadry.

关 键 词：抗骨增止疼片 欧巴代 薄膜包衣 

分 类 号：R942[医药卫生—药剂学]